DIS3L DIS3 like exosome 3'-5' exoribonuclease [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: DIS3Lprovided by VGNC
Official Full Name: DIS3 like exosome 3'-5' exoribonucleaseprovided by VGNC
Primary source: VGNC:VGNC:28073
See related: Ensembl:ENSBTAG00000000371
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	10	NC_037337.1 (13201806..13234118)

Chromosome 10 - NC_037337.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 3'-5'-RNA exonuclease activity	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in rRNA catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cytoplasmic exosome (RNase complex)	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DIS3-like exonuclease 1

Names: DIS3 mitotic control homolog-like

NP_001071624.1

EC 3.1.13.1

XP_024853642.1

EC 3.1.13.1

XP_059746664.1

EC 3.1.13.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001078156.2 → NP_001071624.1 DIS3-like exonuclease 1

See identical proteins and their annotated locations for NP_001071624.1

Status: PROVISIONAL

Source sequence(s)

BC126555

UniProtKB/TrEMBL

A0AAA9SJX3

Related

ENSBTAP00000000481.6, ENSBTAT00000000481.7

Conserved Domains (3) summary

TIGR00358
Location:140 → 816

3_prime_RNase; VacB and RNase II family 3'-5' exoribonucleases

pfam00773
Location:382 → 732

RNB; RNB domain

cl14812
Location:2 → 105

PIN_SF; PIN (PilT N terminus) domain: Superfamily

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

Range

13201806..13234118

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_059890681.1 → XP_059746664.1 DIS3-like exonuclease 1 isoform X1
XM_024997874.1 → XP_024853642.1 DIS3-like exonuclease 1 isoform X2

Conserved Domains (1) summary

COG0557
Location:19 → 604

VacB; Exoribonuclease R [Transcription]