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Steep1 STING1 ER exit protein 1 [ Mus musculus (house mouse) ]

Gene ID: 77644, updated on 26-Sep-2022

Summary

Official Symbol
Steep1provided by MGI
Official Full Name
STING1 ER exit protein 1provided by MGI
Primary source
MGI:MGI:1924894
See related
Ensembl:ENSMUSG00000006423 AllianceGenome:MGI:1924894
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
STEEP; C330007P06Rik
Summary
Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum to Golgi vesicle-mediated transport. Located in cell body and nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 107. Orthologous to human STEEP1 (STING1 ER exit protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 5.6), cerebellum adult (RPKM 5.2) and 28 other tissues See more
Orthologs
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Genomic context

See Steep1 in Genome Data Viewer
Location:
X; X A3.3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (36087388..36127956, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (36827161..36864303, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 Neighboring gene mitochondrial dynamic related lncRNA Neighboring gene 60S ribosomal protein L39 pseudogene Neighboring gene ubiquitin-conjugating enzyme E2A Neighboring gene NF-kappaB repressing factor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cell body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
STING ER exit protein; UPF0428 protein CXorf56 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029951.1NP_084227.1  STING ER exit protein

    See identical proteins and their annotated locations for NP_084227.1

    Status: VALIDATED

    Source sequence(s)
    AK035825, AK036910, BB622061, D18428
    Consensus CDS
    CCDS53050.1
    UniProtKB/Swiss-Prot
    Q8VDP2, Q9CWC1
    UniProtKB/TrEMBL
    A0A6P5P8J1
    Related
    ENSMUSP00000110903.4, ENSMUST00000115248.10

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    36087388..36127956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006541410.5XP_006541473.1  UPF0428 protein CXorf56 homolog isoform X1