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ZNF217 zinc finger protein 217 [ Homo sapiens (human) ]

Gene ID: 7764, updated on 6-Jan-2019

Summary

Official Symbol
ZNF217provided by HGNC
Official Full Name
zinc finger protein 217provided by HGNC
Primary source
HGNC:HGNC:13009
See related
Ensembl:ENSG00000171940 MIM:602967
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZABC1
Expression
Ubiquitous expression in urinary bladder (RPKM 14.5), spleen (RPKM 14.3) and 25 other tissues See more
Orthologs

Genomic context

See ZNF217 in Genome Data Viewer
Location:
20q13.2
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 20 NC_000020.11 (53567065..53608969, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (52183610..52210801, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene teashirt zinc finger homeobox 2 Neighboring gene uncharacterized LOC105372669 Neighboring gene uncharacterized LOC105372671 Neighboring gene uncharacterized LOC101927770 Neighboring gene uncharacterized LOC105372672 Neighboring gene RNA, U7 small nuclear 14 pseudogene Neighboring gene HNF4 motif-containing MPRA enhancer 186

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
histone deacetylase complex IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nuclear speck IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006526.2NP_006517.1  zinc finger protein 217

    See identical proteins and their annotated locations for NP_006517.1

    Status: VALIDATED

    Source sequence(s)
    AF041259, BC039055
    Consensus CDS
    CCDS13443.1
    UniProtKB/Swiss-Prot
    O75362
    Related
    ENSP00000304308.3, ENST00000302342.3
    Conserved Domains (5) summary
    sd00017
    Location:130150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:473493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472493
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:485510
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:750938
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p12 Primary Assembly

    Range
    53567065..53608969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011529036.1XP_011527338.1  zinc finger protein 217 isoform X1

    See identical proteins and their annotated locations for XP_011527338.1

    UniProtKB/TrEMBL
    H0UI66
    Conserved Domains (6) summary
    COG5048
    Location:468733
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:130150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:473493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472493
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:485510
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:750970
    Atrophin-1; Atrophin-1 family
  2. XM_006723875.2XP_006723938.1  zinc finger protein 217 isoform X1

    See identical proteins and their annotated locations for XP_006723938.1

    UniProtKB/TrEMBL
    H0UI66
    Conserved Domains (6) summary
    COG5048
    Location:468733
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:130150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:473493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472493
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:485510
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:750970
    Atrophin-1; Atrophin-1 family
  3. XM_005260545.4XP_005260602.1  zinc finger protein 217 isoform X1

    See identical proteins and their annotated locations for XP_005260602.1

    UniProtKB/TrEMBL
    H0UI66
    Conserved Domains (6) summary
    COG5048
    Location:468733
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:130150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:473493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472493
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:485510
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:750970
    Atrophin-1; Atrophin-1 family
  4. XM_024451996.1XP_024307764.1  zinc finger protein 217 isoform X1

    Conserved Domains (6) summary
    COG5048
    Location:468733
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:130150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:473493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472493
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:485510
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:750970
    Atrophin-1; Atrophin-1 family
  5. XM_024451997.1XP_024307765.1  zinc finger protein 217 isoform X1

    Conserved Domains (6) summary
    COG5048
    Location:468733
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:130150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:473493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472493
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:485510
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:750970
    Atrophin-1; Atrophin-1 family
  6. XM_024451998.1XP_024307766.1  zinc finger protein 217 isoform X1

    Conserved Domains (6) summary
    COG5048
    Location:468733
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:130150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:473493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472493
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:485510
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:750970
    Atrophin-1; Atrophin-1 family
  7. XM_017028059.2XP_016883548.1  zinc finger protein 217 isoform X2

    UniProtKB/Swiss-Prot
    O75362
    Related
    ENSP00000360526.2, ENST00000371471.6
    Conserved Domains (5) summary
    sd00017
    Location:130150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:473493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472493
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:485510
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:750938
    Atrophin-1; Atrophin-1 family
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