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ZSCAN9 zinc finger and SCAN domain containing 9 [ Homo sapiens (human) ]

Gene ID: 7746, updated on 13-Feb-2019

Summary

Official Symbol
ZSCAN9provided by HGNC
Official Full Name
zinc finger and SCAN domain containing 9provided by HGNC
Primary source
HGNC:HGNC:12984
See related
Ensembl:ENSG00000137185 MIM:602246
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRD51; ZNF193
Expression
Ubiquitous expression in testis (RPKM 5.8), endometrium (RPKM 3.5) and 25 other tissues See more
Orthologs

Genomic context

See ZSCAN9 in Genome Data Viewer
Location:
6p22.1
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 6 NC_000006.12 (28224702..28233487)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (28193029..28201265)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene transfer RNA-Ser (GCT) 5-1 Neighboring gene transducer of ERBB2, 2 pseudogene 1 Neighboring gene zinc finger with KRAB and SCAN domains 4 Neighboring gene NFKB activating protein like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger and SCAN domain-containing protein 9
Names
cell proliferation-inducing gene 12 protein
cell proliferation-inducing protein 12
zinc finger protein 193

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199479.1NP_001186408.1  zinc finger and SCAN domain-containing protein 9 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK226035, AK304013, AU310237
    Consensus CDS
    CCDS56407.1
    UniProtKB/Swiss-Prot
    O15535
    Related
    ENSP00000404074.2, ENST00000425468.6
    Conserved Domains (6) summary
    smart00431
    Location:48160
    SCAN; leucine rich region
    COG5048
    Location:304440
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:307327
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:305327
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:49136
    SCAN; SCAN domain
    pfam13465
    Location:320344
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001199480.1NP_001186409.1  zinc finger and SCAN domain-containing protein 9 isoform 2

    See identical proteins and their annotated locations for NP_001186409.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks a segment in the 5' UTR and an in-frame exon in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1. Variants 2 and 3 encode the same isoform 2.
    Source sequence(s)
    AK226035, AL022393, AU310237
    Consensus CDS
    CCDS4646.1
    UniProtKB/Swiss-Prot
    O15535
    UniProtKB/TrEMBL
    A0A024RCK9
    Related
    ENSP00000433402.1, ENST00000531979.5
    Conserved Domains (3) summary
    smart00431
    Location:48160
    SCAN; leucine rich region
    COG5048
    Location:253389
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:256276
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_006299.4NP_006290.1  zinc finger and SCAN domain-containing protein 9 isoform 2

    See identical proteins and their annotated locations for NP_006290.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1. Variants 2 and 3 encode the same isoform 2.
    Source sequence(s)
    AK226035, AK304013, AU310237, BC010374
    Consensus CDS
    CCDS4646.1
    UniProtKB/Swiss-Prot
    O15535
    UniProtKB/TrEMBL
    A0A024RCK9
    Related
    ENSP00000252207.5, ENST00000252207.9
    Conserved Domains (3) summary
    smart00431
    Location:48160
    SCAN; leucine rich region
    COG5048
    Location:253389
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:256276
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p12 Primary Assembly

    Range
    28224702..28233487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017011267.1XP_016866756.1  zinc finger and SCAN domain-containing protein 9 isoform X4

    UniProtKB/Swiss-Prot
    O15535
    UniProtKB/TrEMBL
    A0A024RCK9
    Conserved Domains (3) summary
    smart00431
    Location:48160
    SCAN; leucine rich region
    COG5048
    Location:253389
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:256276
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_011514875.2XP_011513177.1  zinc finger and SCAN domain-containing protein 9 isoform X1

    Conserved Domains (6) summary
    smart00431
    Location:180292
    SCAN; leucine rich region
    COG5048
    Location:442578
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:445465
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:443465
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:181268
    SCAN; SCAN domain
    pfam13465
    Location:458482
    zf-H2C2_2; Zinc-finger double domain
  3. XM_011514876.2XP_011513178.1  zinc finger and SCAN domain-containing protein 9 isoform X2

    Conserved Domains (6) summary
    smart00431
    Location:180292
    SCAN; leucine rich region
    COG5048
    Location:436572
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:439459
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:437459
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:181268
    SCAN; SCAN domain
    pfam13465
    Location:452476
    zf-H2C2_2; Zinc-finger double domain
  4. XM_011514878.2XP_011513180.1  zinc finger and SCAN domain-containing protein 9 isoform X3

    Conserved Domains (6) summary
    smart00431
    Location:180292
    SCAN; leucine rich region
    COG5048
    Location:385521
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:388408
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:386408
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:181268
    SCAN; SCAN domain
    pfam13465
    Location:401425
    zf-H2C2_2; Zinc-finger double domain
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