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Spinkl serine protease inhibitor, Kazal type-like [ Mus musculus (house mouse) ]

Gene ID: 77424, updated on 26-Sep-2022

Summary

Official Symbol
Spinklprovided by MGI
Official Full Name
serine protease inhibitor, Kazal type-likeprovided by MGI
Primary source
MGI:MGI:1924674
See related
Ensembl:ENSMUSG00000053729 AllianceGenome:MGI:1924674
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9530002K18Rik
Summary
Acts upstream of or within negative regulation of sperm capacitation and positive regulation of flagellated sperm motility. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Spinkl in Genome Data Viewer
Location:
18; 18 B3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (44299425..44309774, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (44166358..44176707, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 37797 Neighboring gene predicted gene 10267 Neighboring gene serine peptidase inhibitor, Kazal type 11 Neighboring gene predicted gene, 41716 Neighboring gene neuropeptide Y receptor Y6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General protein information

Preferred Names
serine protease inhibitor kazal-like protein, minor form
Names
SPINKL, minor form

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183123.2NP_898946.1  serine protease inhibitor kazal-like protein, minor form precursor

    See identical proteins and their annotated locations for NP_898946.1

    Status: VALIDATED

    Source sequence(s)
    AK020535
    Consensus CDS
    CCDS50273.1
    UniProtKB/Swiss-Prot
    Q8CEK3
    Related
    ENSMUSP00000063376.4, ENSMUST00000066328.5
    Conserved Domains (1) summary
    cd00104
    Location:4874
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    44299425..44309774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526352.4XP_006526415.1  serine protease inhibitor kazal-like protein, minor form isoform X1

    See identical proteins and their annotated locations for XP_006526415.1

    UniProtKB/Swiss-Prot
    Q8CEK3
    Conserved Domains (1) summary
    cd00104
    Location:4874
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...