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LHX6 LIM homeobox 6 [ Gallus gallus (chicken) ]

Gene ID: 772259, updated on 5-Mar-2024

Summary

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Symbol
LHX6provided by CGNC
Full Name
LIM homeobox 6provided by CGNC
Primary source
CGNC:924
See related
Ensembl:ENSGALG00010027906
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
10
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (9327241..9341479, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (8737717..8752010, complement)

Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like Neighboring gene NADH:ubiquinone oxidoreductase subunit A8 Neighboring gene MORN repeat containing 5 Neighboring gene RNA binding motif protein 18 Neighboring gene uncharacterized LOC107052228 Neighboring gene mitochondrial ribosome recycling factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of cLhx6 and cLhx7/8 suggests a pallido-pedunculo-preoptic origin for the lateral and medial parts of the avian bed nucleus of the stria terminalis. Abellán A, et al. Brain Res Bull, 2008 Mar 18. PMID 18331888
  2. Expression profiles of cIRF6, cLHX6 and cLHX7 in the facial primordia suggest specific roles during primary palatogenesis. Washbourne BJ, et al. BMC Dev Biol, 2006 Mar 24. PMID 16563169, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Our results indicate that these genes are expressed in a subpallial subdomain partially overlapping the expression of Nkx2.1, which includes pallidal, peduncular, commissural preoptic and pallidoseptal subdivisions comparable to those of mammals.
    Title: Expression of cLhx6 and cLhx7/8 suggests a pallido-pedunculo-preoptic origin for the lateral and medial parts of the avian bed nucleus of the stria terminalis.
  2. The restricted expression of both LHX genes and IRF6 in the facial primordia suggests roles for these gene products in promoting directed outgrowth and fusion of the primary palate.
    Title: Expression profiles of cIRF6, cLHX6 and cLHX7 in the facial primordia suggest specific roles during primary palatogenesis.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in forebrain neuron development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LIM/homeobox protein Lhx6
Names
LIM homeodomain protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    9327241..9341479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015279838.4 → XP_015135324.1  LIM/homeobox protein Lhx6

    UniProtKB/TrEMBL
    A0A8V1A648
    Related
    ENSGALP00010041388.1, ENSGALT00010067645.1
    Conserved Domains (3) summary
    cd09380
    Location:120 → 173
    LIM1_Lhx6; The first LIM domain of Lhx6
    cd09382
    Location:181 → 235
    LIM2_Lhx6; The second LIM domain of Lhx6
    pfam00046
    Location:273 → 326
    Homeobox; Homeobox domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    8737717..8752010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040685508.2 → XP_040541442.1  LIM/homeobox protein Lhx6

    UniProtKB/TrEMBL
    A0A8V1A648
    Conserved Domains (3) summary
    cd09380
    Location:120 → 173
    LIM1_Lhx6; The first LIM domain of Lhx6
    cd09382
    Location:181 → 235
    LIM2_Lhx6; The second LIM domain of Lhx6
    pfam00046
    Location:273 → 326
    Homeobox; Homeobox domain
Nucleotide Protein
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