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hlyB hemolysin transport protein [ Escherichia coli ]

Gene ID: 7701380, discontinued on 15-Jul-2020

This record was discontinued.

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Summary

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Gene symbol: hlyB
Gene description: hemolysin transport protein
Locus tag: p026VIR_p016
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli (strain: H30)
Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
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Genomic context

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Location:: plasmid: pO26-Vir

Sequence:: NC_012487.1 (15629..17749)

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_012487.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results provide evidence that the H-loop residue H662 in HlyB-nucleotide binding domain catalyzes ATP hydrolysis by providing a "chemical linchpin" for assisted proton transfer.
Title: Mapping Free Energy Pathways for ATP Hydrolysis in the E. coli ABC Transporter HlyB by the String Method.
Identified are specific regions that respond to ATP hydrolysis, in particular the X-loop motif of ABC exporters, which has been shown to be in contact with the coupling helices of the transmembrane domains.
Title: Structural consequences of ATP hydrolysis on the ABC transporter NBD dimer: molecular dynamics studies of HlyB.

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General protein information

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Preferred Names: hemolysin transport protein

YP_002756567.1

HlyB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_012487.1 Reference assembly

Range

15629..17749

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

YP_002756567.1 hemolysin transport protein [Escherichia coli]

Status: PROVISIONAL

Nucleotide		Protein
Heading	Accession and Version	Protein

Additional links

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Supplemental Content