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Bcas1 brain enriched myelin associated protein 1 [ Mus musculus (house mouse) ]

Gene ID: 76960, updated on 18-Apr-2024

Summary

Official Symbol
Bcas1provided by MGI
Official Full Name
brain enriched myelin associated protein 1provided by MGI
Primary source
MGI:MGI:1924210
See related
Ensembl:ENSMUSG00000013523 AllianceGenome:MGI:1924210
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NABC1; 2210416M21Rik; 9030223A09Rik
Summary
Predicted to enable protein homodimerization activity. Involved in myelination. Predicted to be located in cytosol and postsynaptic density. Orthologous to human BCAS1 (brain enriched myelin associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 42.9), cortex adult (RPKM 25.7) and 6 other tissues See more
Orthologs
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Genomic context

Location:
2 H3; 2 91.41 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (170188911..170270292, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (170343973..170427911, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1017 Neighboring gene predicted gene, 34542 Neighboring gene predicted gene, 39999 Neighboring gene brain enriched myelin associated protein 1, opposite strand 2 Neighboring gene brain enriched myelin associated protein 1, opposite strand 1 Neighboring gene STARR-seq mESC enhancer starr_06529 Neighboring gene predicted gene 14269 Neighboring gene predicted gene, 34608

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (4) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
involved_in myelination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in myelination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
breast carcinoma-amplified sequence 1 homolog
Names
amplified in breast cancer 1
breast carcinoma amplified sequence 1
novel amplified in breast cancer 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164369.1NP_001157841.1  breast carcinoma-amplified sequence 1 homolog isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AL928812, AL935134
    Consensus CDS
    CCDS50806.1
    UniProtKB/TrEMBL
    E9Q8Q5, Q14CE2
    Related
    ENSMUSP00000104780.3, ENSMUST00000109152.9
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunits gamma and tau; Provisional
  2. NM_029815.2NP_084091.2  breast carcinoma-amplified sequence 1 homolog isoform 1

    See identical proteins and their annotated locations for NP_084091.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK008957, AL928812, AL935134, BY720653
    Consensus CDS
    CCDS17121.1
    UniProtKB/Swiss-Prot
    A2AVX2, Q80YN3, Q9CVA1
    UniProtKB/TrEMBL
    Q14CE2
    Related
    ENSMUSP00000013667.3, ENSMUST00000013667.3
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunits gamma and tau; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    170188911..170270292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252201.2XP_030108061.1  breast carcinoma-amplified sequence 1 homolog isoform X13

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  2. XM_030252199.2XP_030108059.1  breast carcinoma-amplified sequence 1 homolog isoform X11

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  3. XM_017319334.2XP_017174823.1  breast carcinoma-amplified sequence 1 homolog isoform X12

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  4. XM_036162697.1XP_036018590.1  breast carcinoma-amplified sequence 1 homolog isoform X5

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  5. XM_017319333.2XP_017174822.1  breast carcinoma-amplified sequence 1 homolog isoform X10

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  6. XM_017319331.2XP_017174820.1  breast carcinoma-amplified sequence 1 homolog isoform X7

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  7. XM_036162696.1XP_036018589.1  breast carcinoma-amplified sequence 1 homolog isoform X3

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  8. XM_030252198.2XP_030108058.1  breast carcinoma-amplified sequence 1 homolog isoform X1

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  9. XM_006500387.3XP_006500450.1  breast carcinoma-amplified sequence 1 homolog isoform X9

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  10. XM_017319330.2XP_017174819.1  breast carcinoma-amplified sequence 1 homolog isoform X6

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  11. XM_017319332.2XP_017174821.1  breast carcinoma-amplified sequence 1 homolog isoform X8

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  12. XM_017319329.3XP_017174818.1  breast carcinoma-amplified sequence 1 homolog isoform X4

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau
  13. XM_036162695.1XP_036018588.1  breast carcinoma-amplified sequence 1 homolog isoform X2

    UniProtKB/TrEMBL
    Q14CE2
    Conserved Domains (1) summary
    PRK12323
    Location:82275
    PRK12323; DNA polymerase III subunit gamma/tau