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Mnd1 meiotic nuclear divisions 1 [ Mus musculus (house mouse) ]

Gene ID: 76915, updated on 8-Feb-2024

Summary

Official Symbol
Mnd1provided by MGI
Official Full Name
meiotic nuclear divisions 1provided by MGI
Primary source
MGI:MGI:1924165
See related
Ensembl:ENSMUSG00000033752 AllianceGenome:MGI:1924165
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gaj; 2610034E18Rik
Summary
Predicted to enable double-stranded DNA binding activity. Predicted to be involved in reciprocal meiotic recombination. Predicted to act upstream of or within DNA recombination and meiotic cell cycle. Predicted to be active in nucleus. Is expressed in branchial arch; central nervous system; embryo; forelimb bud; and somite. Orthologous to human MND1 (meiotic nuclear divisions 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver E14 (RPKM 3.5), CNS E11.5 (RPKM 3.0) and 17 other tissues See more
Orthologs
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Genomic context

See Mnd1 in Genome Data Viewer
Location:
3 F1; 3 37.46 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (83995240..84063084, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (84087933..84155798, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4548 Neighboring gene predicted gene, 30352 Neighboring gene STARR-positive B cell enhancer ABC_E3440 Neighboring gene predicted gene, 30458 Neighboring gene STARR-positive B cell enhancer ABC_E7917 Neighboring gene STARR-positive B cell enhancer ABC_E9214 Neighboring gene STARR-positive B cell enhancer ABC_E1020 Neighboring gene STARR-seq mESC enhancer starr_08077 Neighboring gene tripartite motif-containing 2 Neighboring gene STARR-seq mESC enhancer starr_08078 Neighboring gene ribosomal protein L36a pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr3:84032505-84032806 Neighboring gene nuclear encoded tRNA glycine 9 (anticodon GCC) Neighboring gene predicted gene, 40078

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in homologous chromosome pairing at meiosis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in reciprocal meiotic recombination ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
meiotic nuclear division protein 1 homolog
Names
meiotic nuclear divisions 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398662.1NP_001385591.1  meiotic nuclear division protein 1 homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154875
    Conserved Domains (1) summary
    COG5124
    Location:5179
    COG5124; Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only]
  2. NM_029797.4NP_084073.2  meiotic nuclear division protein 1 homolog isoform 1

    See identical proteins and their annotated locations for NP_084073.2

    Status: VALIDATED

    Source sequence(s)
    AC154875
    Consensus CDS
    CCDS38464.1
    UniProtKB/Swiss-Prot
    Q8K396, Q9D0A1
    Related
    ENSMUSP00000048262.7, ENSMUST00000047368.8
    Conserved Domains (2) summary
    COG5124
    Location:5204
    COG5124; Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only]
    pfam03962
    Location:16202
    Mnd1; Mnd1 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    83995240..84063084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163403.1XP_036019296.1  meiotic nuclear division protein 1 homolog isoform X1

    Conserved Domains (1) summary
    COG5124
    Location:1189
    COG5124; Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only]