U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ssbp4 single stranded DNA binding protein 4 [ Mus musculus (house mouse) ]

Gene ID: 76900, updated on 5-Mar-2024

Summary

Official Symbol
Ssbp4provided by MGI
Official Full Name
single stranded DNA binding protein 4provided by MGI
Primary source
MGI:MGI:1924150
See related
Ensembl:ENSMUSG00000070003 AllianceGenome:MGI:1924150
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ssdp4; Sspb4; 1210002E11Rik
Summary
Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in gonad; limb; retina; telencephalon; and trunk somite. Orthologous to human SSBP4 (single stranded DNA binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 126.2), ovary adult (RPKM 102.6) and 27 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ssbp4 in Genome Data Viewer
Location:
8 B3.3; 8 34.15 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (71050135..71061084, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (70597485..70608387, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene elongation factor RNA polymerase II Neighboring gene STARR-positive B cell enhancer ABC_E1369 Neighboring gene myo-inositol 1-phosphate synthase A1 Neighboring gene STARR-positive B cell enhancer ABC_E3777 Neighboring gene STARR-positive B cell enhancer ABC_E3778 Neighboring gene STARR-positive B cell enhancer ABC_E3779 Neighboring gene leucine rich repeat containing 25 Neighboring gene STARR-positive B cell enhancer ABC_E6645 Neighboring gene STARR-seq mESC enhancer starr_21778 Neighboring gene growth differentiation factor 15

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
single-stranded DNA-binding protein 4

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001372468.1NP_001359397.1  single-stranded DNA-binding protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC157774
    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81366
    SSDP; Single-stranded DNA binding protein, SSDP
  2. NM_001372469.1NP_001359398.1  single-stranded DNA-binding protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC157774
    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81346
    SSDP; Single-stranded DNA binding protein, SSDP
  3. NM_001372470.1NP_001359399.1  single-stranded DNA-binding protein 4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC157774
    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81366
    SSDP; Single-stranded DNA binding protein, SSDP
  4. NM_001372471.1NP_001359400.1  single-stranded DNA-binding protein 4 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC157774
    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81338
    SSDP; Single-stranded DNA binding protein, SSDP
  5. NM_001372472.1NP_001359401.1  single-stranded DNA-binding protein 4 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC157774
    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81338
    SSDP; Single-stranded DNA binding protein, SSDP
  6. NM_001372473.1NP_001359402.1  single-stranded DNA-binding protein 4 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC157774
    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81356
    SSDP; Single-stranded DNA binding protein, SSDP
  7. NM_001372475.1NP_001359404.1  single-stranded DNA-binding protein 4 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC157774
    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81318
    SSDP; Single-stranded DNA binding protein, SSDP
  8. NM_001372476.1NP_001359405.1  single-stranded DNA-binding protein 4 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC157774
    UniProtKB/TrEMBL
    A0A1B0GRX5
    Related
    ENSMUSP00000147704.2, ENSMUST00000210369.2
    Conserved Domains (1) summary
    pfam04503
    Location:1237
    SSDP; Single-stranded DNA binding protein, SSDP
  9. NM_001372477.1NP_001359406.1  single-stranded DNA-binding protein 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC157774
    Conserved Domains (1) summary
    pfam04503
    Location:1237
    SSDP; Single-stranded DNA binding protein, SSDP
  10. NM_001372478.1NP_001359407.1  single-stranded DNA-binding protein 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC157774
    Conserved Domains (1) summary
    pfam04503
    Location:1237
    SSDP; Single-stranded DNA binding protein, SSDP
  11. NM_001372479.1NP_001359408.1  single-stranded DNA-binding protein 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC157774
    Conserved Domains (1) summary
    pfam04503
    Location:1237
    SSDP; Single-stranded DNA binding protein, SSDP
  12. NM_133772.3NP_598533.2  single-stranded DNA-binding protein 4 isoform 6

    See identical proteins and their annotated locations for NP_598533.2

    Status: VALIDATED

    Source sequence(s)
    AC157774
    Consensus CDS
    CCDS22374.1
    UniProtKB/TrEMBL
    Q3U4B1, Q99LZ8
    Related
    ENSMUSP00000059039.10, ENSMUST00000049908.11
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81338
    SSDP; Single-stranded DNA binding protein, SSDP

RNA

  1. NR_164176.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157774
    Related
    ENSMUST00000211134.2
  2. NR_164177.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157774
  3. NR_164178.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157774

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    71050135..71061084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242338.4XP_011240640.1  single-stranded DNA-binding protein 4 isoform X6

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81346
    SSDP; Single-stranded DNA binding protein, SSDP
  2. XM_036154374.1XP_036010267.1  single-stranded DNA-binding protein 4 isoform X5

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81356
    SSDP; Single-stranded DNA binding protein, SSDP
  3. XM_011242337.4XP_011240639.1  single-stranded DNA-binding protein 4 isoform X4

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81384
    SSDP; Single-stranded DNA binding protein, SSDP
  4. XM_006509784.5XP_006509847.1  single-stranded DNA-binding protein 4 isoform X1

    See identical proteins and their annotated locations for XP_006509847.1

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81384
    SSDP; Single-stranded DNA binding protein, SSDP
  5. XM_036154375.1XP_036010268.1  single-stranded DNA-binding protein 4 isoform X7

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81318
    SSDP; Single-stranded DNA binding protein, SSDP
  6. XM_030243848.2XP_030099708.1  single-stranded DNA-binding protein 4 isoform X7

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81318
    SSDP; Single-stranded DNA binding protein, SSDP
  7. XM_011242336.4XP_011240638.1  single-stranded DNA-binding protein 4 isoform X3

    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81364
    SSDP; Single-stranded DNA binding protein, SSDP
  8. XM_006509790.5XP_006509853.1  single-stranded DNA-binding protein 4 isoform X5

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81356
    SSDP; Single-stranded DNA binding protein, SSDP
  9. XM_036154372.1XP_036010265.1  single-stranded DNA-binding protein 4 isoform X1

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81384
    SSDP; Single-stranded DNA binding protein, SSDP
  10. XM_036154376.1XP_036010269.1  single-stranded DNA-binding protein 4 isoform X8

    Conserved Domains (1) summary
    pfam04503
    Location:45290
    SSDP; Single-stranded DNA binding protein, SSDP
  11. XM_036154373.1XP_036010266.1  single-stranded DNA-binding protein 4 isoform X2

    UniProtKB/TrEMBL
    Q99LZ8
    Conserved Domains (2) summary
    smart00667
    Location:1743
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:81366
    SSDP; Single-stranded DNA binding protein, SSDP