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Memo1 mediator of cell motility 1 [ Mus musculus (house mouse) ]

Gene ID: 76890, updated on 26-Sep-2022

Summary

Official Symbol
Memo1provided by MGI
Official Full Name
mediator of cell motility 1provided by MGI
Primary source
MGI:MGI:1924140
See related
Ensembl:ENSMUSG00000058704 AllianceGenome:MGI:1924140
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
0610016J10Rik; D930048L02Rik
Summary
Predicted to enable peptide binding activity. Predicted to be involved in regulation of microtubule-based process. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human MEMO1 (mediator of cell motility 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 11.5), liver E14 (RPKM 11.0) and 28 other tissues See more
Orthologs
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Genomic context

See Memo1 in Genome Data Viewer
Location:
17; 17 E2
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (74493759..74602677, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (74186764..74295682, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31235 Neighboring gene predicted gene, 53978 Neighboring gene F-box protein 34 pseudogene Neighboring gene predicted gene, 52299 Neighboring gene dpy-30, histone methyltransferase complex regulatory subunit Neighboring gene predicted gene, 31328

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Chemically induced (ENU) (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables peptide binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of microtubule-based process ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein MEMO1
Names
mediator of ErbB2-driven cell motility 1
memo-1
protein memo

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133771.2NP_598532.1  protein MEMO1

    See identical proteins and their annotated locations for NP_598532.1

    Status: VALIDATED

    Source sequence(s)
    AF363447, BF466279, CT010445
    Consensus CDS
    CCDS28969.1
    UniProtKB/Swiss-Prot
    Q91VH6
    UniProtKB/TrEMBL
    A0A6P5R9N7
    Related
    ENSMUSP00000156607.2, ENSMUST00000233514.3
    Conserved Domains (1) summary
    cd07361
    Location:9294
    MEMO_like; Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    74493759..74602677 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525109.5XP_006525172.1  protein MEMO1 isoform X1

    See identical proteins and their annotated locations for XP_006525172.1

    UniProtKB/Swiss-Prot
    Q91VH6
    UniProtKB/TrEMBL
    A0A6P5R9N7
    Conserved Domains (1) summary
    cd07361
    Location:9294
    MEMO_like; Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility
  2. XM_036160831.1XP_036016724.1  protein MEMO1 isoform X2

    UniProtKB/TrEMBL
    A0A3B2W7C9
    Related
    ENSMUSP00000156437.2, ENSMUST00000232989.2
    Conserved Domains (1) summary
    cd07361
    Location:9219
    MEMO_like; Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility
  3. XM_011246713.4XP_011245015.1  protein MEMO1 isoform X3

    See identical proteins and their annotated locations for XP_011245015.1

    Conserved Domains (1) summary
    cl00599
    Location:114198
    Extradiol_Dioxygenase_3B_like; Subunit B of Class III Extradiol ring-cleavage dioxygenases

RNA

  1. XR_003952211.2 RNA Sequence

  2. XR_385387.5 RNA Sequence