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Mtfr1l mitochondrial fission regulator 1-like [ Mus musculus (house mouse) ]

Gene ID: 76824, updated on 26-Sep-2022

Summary

Official Symbol
Mtfr1lprovided by MGI
Official Full Name
mitochondrial fission regulator 1-likeprovided by MGI
Primary source
MGI:MGI:1924074
See related
Ensembl:ENSMUSG00000046671 AllianceGenome:MGI:1924074
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam54b; 2410166I05Rik
Summary
Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be active in mitochondrion. Orthologous to human MTFR1L (mitochondrial fission regulator 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 60.2), heart adult (RPKM 44.5) and 28 other tissues See more
Orthologs
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Genomic context

See Mtfr1l in Genome Data Viewer
Location:
4; 4 D3
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (134252866..134262698, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134525555..134535387, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene progestin and adipoQ receptor family member VII Neighboring gene aurora kinase A and ninein interacting protein Neighboring gene selenoprotein N Neighboring gene mannosidase, alpha, class 1C, member 1 Neighboring gene microRNA 6403

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in aerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitochondrial fission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
mitochondrial fission regulator 1-like
Names
family with sequence similarity 54, member B
protein FAM54B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256112.1NP_001243041.1  mitochondrial fission regulator 1-like

    See identical proteins and their annotated locations for NP_001243041.1

    Status: VALIDATED

    Source sequence(s)
    AI836704, AK145362, BY094859
    Consensus CDS
    CCDS18775.1
    UniProtKB/Swiss-Prot
    Q8BTP7, Q9CWE0
    UniProtKB/TrEMBL
    A0A8C6GAE8
    Related
    ENSMUSP00000099609.4, ENSMUST00000102550.10
    Conserved Domains (1) summary
    pfam05308
    Location:9250
    Mito_fiss_reg; Mitochondrial fission regulator
  2. NM_001355187.1NP_001342116.1  mitochondrial fission regulator 1-like

    Status: VALIDATED

    Source sequence(s)
    AI836704, AK169047, BY295153
    Consensus CDS
    CCDS18775.1
    UniProtKB/Swiss-Prot
    Q8BTP7
    UniProtKB/TrEMBL
    A0A8C6GAE8
    Conserved Domains (1) summary
    pfam05308
    Location:9250
    Mito_fiss_reg; Mitochondrial fission regulator
  3. NM_001355188.1NP_001342117.1  mitochondrial fission regulator 1-like

    Status: VALIDATED

    Source sequence(s)
    AI836704, AK169047, AL669982, BY261234, CX200239
    Consensus CDS
    CCDS18775.1
    UniProtKB/Swiss-Prot
    Q8BTP7
    UniProtKB/TrEMBL
    A0A8C6GAE8
    Conserved Domains (1) summary
    pfam05308
    Location:9250
    Mito_fiss_reg; Mitochondrial fission regulator
  4. NM_029759.4NP_084035.1  mitochondrial fission regulator 1-like

    See identical proteins and their annotated locations for NP_084035.1

    Status: VALIDATED

    Source sequence(s)
    AI836704, AK169047, BY123213
    Consensus CDS
    CCDS18775.1
    UniProtKB/Swiss-Prot
    Q8BTP7, Q9CWE0
    UniProtKB/TrEMBL
    A0A8C6GAE8
    Related
    ENSMUSP00000111983.4, ENSMUST00000116279.10
    Conserved Domains (1) summary
    pfam05308
    Location:9250
    Mito_fiss_reg; Mitochondrial fission regulator

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    134252866..134262698 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539256.2XP_006539319.1  mitochondrial fission regulator 1-like isoform X1

    See identical proteins and their annotated locations for XP_006539319.1

    UniProtKB/Swiss-Prot
    Q8BTP7, Q9CWE0
    UniProtKB/TrEMBL
    A0A8C6GAE8
    Related
    ENSMUSP00000117943.2, ENSMUST00000154769.8
    Conserved Domains (1) summary
    pfam05308
    Location:9250
    Mito_fiss_reg; Mitochondrial fission regulator
  2. XM_006539258.3XP_006539321.1  mitochondrial fission regulator 1-like isoform X1

    See identical proteins and their annotated locations for XP_006539321.1

    UniProtKB/Swiss-Prot
    Q8BTP7, Q9CWE0
    UniProtKB/TrEMBL
    A0A8C6GAE8
    Conserved Domains (1) summary
    pfam05308
    Location:9250
    Mito_fiss_reg; Mitochondrial fission regulator