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RELL1 RELT like 1 [ Homo sapiens (human) ]

Gene ID: 768211, updated on 22-Aug-2020

Summary

Official Symbol
RELL1provided by HGNC
Official Full Name
RELT like 1provided by HGNC
Primary source
HGNC:HGNC:27379
See related
Ensembl:ENSG00000181826 MIM:611212
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in stomach (RPKM 7.1), thyroid (RPKM 6.7) and 25 other tissues See more
Orthologs

Genomic context

See RELL1 in Genome Data Viewer
Location:
4p14
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (37590804..37686403, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (37592422..37687999, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene microRNA 4801 Neighboring gene NACHT and WD repeat domain containing 2 Neighboring gene Sharpr-MPRA regulatory region 2247 Neighboring gene chromosome 4 open reading frame 19 Neighboring gene HNF4 motif-containing MPRA enhancer 255 Neighboring gene uncharacterized LOC105374404 Neighboring gene uncharacterized LOC105374406

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21778, MGC50583

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
positive regulation of p38MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of p38MAPK cascade IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
microtubule cytoskeleton IDA
Inferred from Direct Assay
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
RELT-like protein 1
Names
receptor expressed in lymphoid tissues like 1
tmp_locus_29

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085399.2NP_001078868.1  RELT-like protein 1 precursor

    See identical proteins and their annotated locations for NP_001078868.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK075468, BC039540, DA400382
    Consensus CDS
    CCDS43221.1
    UniProtKB/Swiss-Prot
    Q8IUW5
    Related
    ENSP00000313385.4, ENST00000314117.8
    Conserved Domains (1) summary
    pfam12606
    Location:5895
    RELT; tumor necrosis factor receptor superfamily member 19
  2. NM_001085400.2NP_001078869.1  RELT-like protein 1 precursor

    See identical proteins and their annotated locations for NP_001078869.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC027607, AC108022
    Consensus CDS
    CCDS43221.1
    UniProtKB/Swiss-Prot
    Q8IUW5
    Related
    ENSP00000398778.2, ENST00000454158.7
    Conserved Domains (1) summary
    pfam12606
    Location:5895
    RELT; tumor necrosis factor receptor superfamily member 19

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    37590804..37686403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008590.2XP_016864079.1  RELT-like protein 1 isoform X1

RNA

  1. XR_002959758.1 RNA Sequence

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