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cnot7 CCR4-NOT transcription complex, subunit 7 [ Danio rerio (zebrafish) ]

Gene ID: 768119, updated on 3-Dec-2024

Summary

Official Symbol
cnot7provided by ZNC
Official Full Name
CCR4-NOT transcription complex, subunit 7provided by ZNC
Primary source
ZFIN:ZDB-GENE-061013-29
See related
Ensembl:ENSDARG00000032116 AllianceGenome:ZFIN:ZDB-GENE-061013-29
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
CAF1; fd59c07; fj07d05; wu:fd59c07; wu:fj07d05; zgc:153168
Summary
Predicted to enable poly(A)-specific ribonuclease activity. Acts upstream of or within mRNA catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. Orthologous to human CNOT7 (CCR4-NOT transcription complex subunit 7). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See cnot7 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (30413753..30424861)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (30073444..30084542)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 7 member 2 Neighboring gene myotubularin related protein 7a Neighboring gene zinc finger DHHC-type palmitoyltransferase 2 Neighboring gene mitochondrial calcium uptake family, member 3b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables exonuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables poly(A)-specific ribonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables poly(A)-specific ribonuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables poly(A)-specific ribonuclease activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of CCR4-NOT complex IEA
Inferred from Electronic Annotation
more info
 
part_of CCR4-NOT complex ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of CCR4-NOT core complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
CCR4-NOT transcription complex subunit 7
Names
CAF-1
CCR4-associated factor 1
NP_001070723.1
XP_021336741.1
XP_068069348.1
XP_068069349.1
XP_068069350.1
XP_068069351.1
XP_068069352.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077255.1NP_001070723.1  CCR4-NOT transcription complex subunit 7

    See identical proteins and their annotated locations for NP_001070723.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124650
    UniProtKB/Swiss-Prot
    Q08BM8
    Related
    ENSDARP00000087385.5, ENSDART00000092953.7
    Conserved Domains (1) summary
    cl23804
    Location:1279
    CAF1; CAF1 family ribonuclease

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    30413753..30424861
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068213247.1XP_068069348.1  CCR4-NOT transcription complex subunit 7 isoform X1

  2. XM_068213248.1XP_068069349.1  CCR4-NOT transcription complex subunit 7 isoform X2

  3. XM_021481066.2XP_021336741.1  CCR4-NOT transcription complex subunit 7 isoform X3

    UniProtKB/TrEMBL
    A0A8M9QKP5
    Conserved Domains (1) summary
    cl23804
    Location:1288
    CAF1; CAF1 family ribonuclease
  4. XM_068213251.1XP_068069352.1  CCR4-NOT transcription complex subunit 7 isoform X6

    UniProtKB/TrEMBL
    A0A8M9QB61
  5. XM_068213250.1XP_068069351.1  CCR4-NOT transcription complex subunit 7 isoform X5

    Related
    ENSDARP00000113903.1, ENSDART00000136009.2
  6. XM_068213249.1XP_068069350.1  CCR4-NOT transcription complex subunit 7 isoform X4

    UniProtKB/Swiss-Prot
    Q08BM8
    Related
    ENSDARP00000156128.1, ENSDART00000186864.1

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394914.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    343937..354772
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)