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FBXW2 F-box and WD repeat domain containing 2 [ Bos taurus (domestic cattle) ]

Gene ID: 767863, updated on 5-Aug-2026
Official Symbol
FBXW2provided by VGNC
Official Full Name
F-box and WD repeat domain containing 2provided by VGNC
Primary source
VGNC:VGNC:28923
See related
BGD:BT25537; Ensembl:ENSBTAG00070014747
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
all
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Try the new Transcripts and proteins table
See FBXW2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (110162116..110188748, complement)

Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene multiple EGF like domains 9 Neighboring gene uncharacterized LOC132346022 Neighboring gene beta-1,3-galactosyltransferase 9 Neighboring gene proteasome 26S subunit, non-ATPase 5

Genomic Sequence:
NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
F-box/WD repeat-containing protein 2
Names
F-box and WD-40 domain protein 2
F-box and WD-40 domain-containing protein 2

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076974.1 → NP_001070442.1  F-box/WD repeat-containing protein 2

    See identical proteins and their annotated locations for NP_001070442.1

    Status: PROVISIONAL

    Source sequence(s)
    BC120224
    UniProtKB/Swiss-Prot
    Q58D00, Q58DP3
    Conserved Domains (4) summary
    smart00256
    Location:60 → 94
    FBOX; A Receptor for Ubiquitination Targets
    COG2319
    Location:140 → 401
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:140 → 447
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:151 → 185
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    110162116..110188748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059889267.1 → XP_059745250.1  F-box/WD repeat-containing protein 2 isoform X5

  2. XM_059889266.1 → XP_059745249.1  F-box/WD repeat-containing protein 2 isoform X2

    UniProtKB/Swiss-Prot
    Q58D00, Q58DP3

  3. XM_024995968.2 → XP_024851736.1  F-box/WD repeat-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0AAF7ADU5
    Related
    ENSBTAP00070019701.1, ENSBTAT00070033382.1
    Conserved Domains (3) summary
    smart00256
    Location:70 → 104
    FBOX; A Receptor for Ubiquitination Targets
    sd00039
    Location:161 → 195
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:150 → 364
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_024995967.2 → XP_024851735.1  F-box/WD repeat-containing protein 2 isoform X1

    Conserved Domains (3) summary
    smart00256
    Location:70 → 104
    FBOX; A Receptor for Ubiquitination Targets
    cd00200
    Location:150 → 457
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:161 → 195
    7WD40; WD40 repeat [structural motif]

  5. XM_024995969.2 → XP_024851737.1  F-box/WD repeat-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0AAF6YHP9
    Related
    ENSBTAP00070019688.1, ENSBTAT00070033363.1
    Conserved Domains (3) summary
    smart00256
    Location:41 → 75
    FBOX; A Receptor for Ubiquitination Targets
    cd00200
    Location:121 → 428
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:132 → 166
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q58D00.1 GenPept UniProtKB/Swiss-Prot:Q58D00

Gene LinkOut

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