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apoda.1 apolipoprotein Da, duplicate 1 [ Danio rerio (zebrafish) ]

Gene ID: 767642, updated on 4-Jan-2025

Summary

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Official Symbol
apoda.1provided by ZNC
Official Full Name
apolipoprotein Da, duplicate 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-148
See related
Ensembl:ENSDARG00000060345 AllianceGenome:ZFIN:ZDB-GENE-060929-148
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
apod; zgc:153593
Summary
Predicted to enable lipid binding activity. Predicted to be involved in lipid metabolic process and response to reactive oxygen species. Predicted to act upstream of or within brain development; lipid transport; and tissue regeneration. Predicted to be located in extracellular region. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human APOD (apolipoprotein D). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See apoda.1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (37207792..37210389, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (37225335..37227932, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 19 Neighboring gene COPI coat complex subunit alpha Neighboring gene apolipoprotein Da, duplicate 2 Neighboring gene sterile alpha motif domain containing 7 Neighboring gene SEC62 homolog, preprotein translocation factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery. Zhang Y, et al. Front Mol Neurosci, 2022. PMID 35686059, Free PMC Article
  2. Environmental estrogen exposure converts lipid metabolism in male fish to a female pattern mediated by AMPK and mTOR signaling pathways. Sun SX, et al. J Hazard Mater, 2020 Jul 15. PMID 32203715
  3. The zebrafish genes encoding the Polycomb repressive complex (PRC) 1. Le Faou P, et al. Gene, 2011 Apr 1. PMID 21195142
  4. A temporal single cell transcriptome atlas of zebrafish anterior segment development. Vöcking O, et al. Sci Rep, 2023 Apr 6. PMID 37024546, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC153593

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within brain development IEA
Inferred from Electronic Annotation
more info
  
involved_in lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in response to reactive oxygen species IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within tissue regeneration IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
apolipoprotein Da, duplicate 1
Names
apoda
apolipoprotein D

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076582.2 → NP_001070050.2  apolipoprotein Da, duplicate 1 precursor

    Status: VALIDATED

    Source sequence(s)
    EH475543
    UniProtKB/TrEMBL
    A0A8M1NAX4, F1R0I2
    Related
    ENSDARP00000079373.4, ENSDART00000084938.5
    Conserved Domains (1) summary
    cl21528
    Location:34 → 178
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    37207792..37210389 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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