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Clasp1 CLIP associating protein 1 [ Mus musculus (house mouse) ]

Gene ID: 76707, updated on 21-Mar-2023

Summary

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Official Symbol
Clasp1provided by MGI
Official Full Name
CLIP associating protein 1provided by MGI
Primary source
MGI:MGI:1923957
See related
Ensembl:ENSMUSG00000064302 AllianceGenome:MGI:1923957
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CLASP1alpha; 1700030C23Rik; 5730583A19Rik; B130045P17Rik
Summary
Enables microtubule binding activity. Acts upstream of or within negative regulation of microtubule depolymerization. Located in microtubule cytoskeleton. Is expressed in gastrocnemius muscle. Orthologous to human CLASP1 (cytoplasmic linker associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in heart adult (RPKM 33.1), whole brain E14.5 (RPKM 17.4) and 27 other tissues See more
Orthologs
human all
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Genomic context

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See Clasp1 in Genome Data Viewer
Location:
1; 1 E2.3
Exon count:
45
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (118314976..118537192)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (118389058..118609462)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene nucleolar protein interacting with the FHA domain of MKI67 Neighboring gene predicted gene 28867 Neighboring gene RIKEN cDNA 2900060B14 gene Neighboring gene predicted gene, 26080 Neighboring gene transcription factor CP2-like 1 Neighboring gene U1 spliceosomal RNA Neighboring gene GLI-Kruppel family member GLI2 Neighboring gene predicted gene, 51642 Neighboring gene microRNA 6346

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. GSK3 controls axon growth via CLASP-mediated regulation of growth cone microtubules. Hur EM, et al. Genes Dev, 2011 Sep 15. PMID 21937714, Free PMC Article
  2. RNA-seq analysis of developing olfactory bulb projection neurons. Kawasawa YI, et al. Mol Cell Neurosci, 2016 Jul. PMID 27073125, Free PMC Article
  3. MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis. Samora CP, et al. Nat Cell Biol, 2011 Aug 7. PMID 21822276
  4. Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells. Lim BC, et al. J Cell Sci, 2016 Aug 15. PMID 27378169
  5. Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions. Brinegar AE, et al. Elife, 2017 Aug 11. PMID 28826478, Free PMC Article

See all (37) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0622, mKIAA0622

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables dystroglycan binding ISO
Inferred from Sequence Orthology
more info
  
enables kinetochore binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables kinetochore binding ISO
Inferred from Sequence Orthology
more info
  
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables microtubule binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
enables microtubule plus-end binding ISO
Inferred from Sequence Orthology
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
  
involved_in astral microtubule organization ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell division ISO
Inferred from Sequence Orthology
more info
 PubMed 
involved_in cell migration IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in establishment of cell polarity IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in establishment of mitotic spindle localization IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in establishment of mitotic spindle localization ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within establishment of spindle orientation ISO
Inferred from Sequence Orthology
more info
 PubMed 
involved_in exit from mitosis ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule anchoring ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule bundle formation ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule nucleation ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule organizing center organization ISO
Inferred from Sequence Orthology
more info
  
involved_in mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in mitotic spindle organization ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within negative regulation of microtubule depolymerization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of microtubule depolymerization ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of microtubule polymerization or depolymerization ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of stress fiber assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of wound healing, spreading of epidermal cells ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of basement membrane assembly involved in embryonic body morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of epithelial cell migration ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of exocytosis ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of extracellular matrix disassembly ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of epithelial to mesenchymal transition ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of focal adhesion assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of gastrulation ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
  
involved_in vesicle targeting ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
is_active_in basal cortex IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in basal cortex ISO
Inferred from Sequence Orthology
more info
  
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
  
located_in centrosomal corona ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in cortical microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoplasmic microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with focal adhesion ISO
Inferred from Sequence Orthology
more info
  
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
  
located_in kinetochore microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule cytoskeleton IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in microtubule organizing center IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
is_active_in mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
is_active_in spindle microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in spindle microtubule ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
CLIP-associating protein 1
Names
cytoplasmic linker-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293300.1 → NP_001280229.1  CLIP-associating protein 1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) encodes isoform (4).
    Source sequence(s)
    AC131804, AK042402, BC057312, BC094432, BC094554, BU703855, CF538190, CK640085
    UniProtKB/Swiss-Prot
    Q80TV8
    UniProtKB/TrEMBL
    A0A087WQ31, A5D6Q8
    Related
    ENSMUSP00000140019.2, ENSMUST00000190571.7
    Conserved Domains (2) summary
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]

  2. NM_001293301.1 → NP_001280230.1  CLIP-associating protein 1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks five exons in the central coding regioin, but maintains the reading frame, compared to variant 4. The encoded isoform (5) is shorter, compared to isoform 4.
    Source sequence(s)
    AK042402, BC094432, BC094554, BU703855, CF538190
    UniProtKB/Swiss-Prot
    Q80TV8
    UniProtKB/TrEMBL
    A5D6Q8, E9Q6L0
    Related
    ENSMUSP00000128089.3, ENSMUST00000165223.8
    Conserved Domains (2) summary
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]

  3. NM_001359328.1 → NP_001346257.1  CLIP-associating protein 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 802
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  4. NM_001359329.1 → NP_001346258.1  CLIP-associating protein 1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 817
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  5. NM_001359330.1 → NP_001346259.1  CLIP-associating protein 1 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Related
    ENSMUSP00000042266.7, ENSMUST00000049404.13
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 767
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  6. NM_001359331.1 → NP_001346260.1  CLIP-associating protein 1 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 802
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  7. NM_001359334.1 → NP_001346263.1  CLIP-associating protein 1 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    UniProtKB/TrEMBL
    A0A087WRE8
    Related
    ENSMUSP00000067858.8, ENSMUST00000070989.14
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 817
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  8. NM_001359335.1 → NP_001346264.1  CLIP-associating protein 1 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 802
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  9. NM_001359336.1 → NP_001346265.1  CLIP-associating protein 1 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:649 → 721
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  10. NM_001359337.1 → NP_001346266.1  CLIP-associating protein 1 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 775
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  11. NM_001359338.1 → NP_001346267.1  CLIP-associating protein 1 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:572 → 713
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  12. NM_001359339.1 → NP_001346268.1  CLIP-associating protein 1 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 767
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  13. NM_001359340.1 → NP_001346269.1  CLIP-associating protein 1 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:572 → 713
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  14. NM_001359341.1 → NP_001346270.1  CLIP-associating protein 1 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 767
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  15. NM_001359342.1 → NP_001346271.1  CLIP-associating protein 1 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam05956
    Location:566 → 785
    APC_basic; APC basic domain
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  16. NM_001359343.1 → NP_001346272.1  CLIP-associating protein 1 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 793
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  17. NM_001359345.1 → NP_001346274.1  CLIP-associating protein 1 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    UniProtKB/TrEMBL
    A0A087WRK0
    Related
    ENSMUSP00000140665.3, ENSMUST00000189738.7
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:564 → 780
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  18. NM_001359346.1 → NP_001346275.1  CLIP-associating protein 1 isoform 21

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    UniProtKB/TrEMBL
    A0A087WQ95
    Related
    ENSMUSP00000140095.3, ENSMUST00000191445.7
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    cl28033
    Location:572 → 713
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  19. NM_001359347.1 → NP_001346276.1  CLIP-associating protein 1 isoform 22

    Status: VALIDATED

    Source sequence(s)
    AC109294, AC131804, AC136636
    Conserved Domains (3) summary
    sd00044
    Location:461 → 488
    HEAT; HEAT repeat [structural motif]
    pfam12348
    Location:1 → 127
    CLASP_N; CLASP N terminal
    cl28033
    Location:154 → 365
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  20. NM_029709.2 → NP_083985.2  CLIP-associating protein 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks four exons in the central coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (3) is shorter, compared to isoform 4.
    Source sequence(s)
    AK042402, BC094432, BC094554, BU703855, CF538190
    UniProtKB/Swiss-Prot
    Q80TV8
    UniProtKB/TrEMBL
    A0A087WS18, A5D6Q8
    Related
    ENSMUSP00000140860.3, ENSMUST00000189262.7
    Conserved Domains (2) summary
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    118314976..118537192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529920.2 → XP_006529983.1  CLIP-associating protein 1 isoform X1

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  2. XM_006529929.2 → XP_006529992.1  CLIP-associating protein 1 isoform X5

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  3. XM_006529937.2 → XP_006530000.1  CLIP-associating protein 1 isoform X11

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  4. XM_006529922.2 → XP_006529985.1  CLIP-associating protein 1 isoform X2

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  5. XM_036154261.1 → XP_036010154.1  CLIP-associating protein 1 isoform X7

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  6. XM_036154259.1 → XP_036010152.1  CLIP-associating protein 1 isoform X6

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  7. XM_006529938.2 → XP_006530001.1  CLIP-associating protein 1 isoform X12

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  8. XM_006529924.2 → XP_006529987.1  CLIP-associating protein 1 isoform X3

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  9. XM_006529939.2 → XP_006530002.1  CLIP-associating protein 1 isoform X14

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  10. XM_036154255.1 → XP_036010148.1  CLIP-associating protein 1 isoform X4

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  11. XM_036154262.1 → XP_036010155.1  CLIP-associating protein 1 isoform X8

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  12. XM_030243458.2 → XP_030099318.1  CLIP-associating protein 1 isoform X15

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 810
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  13. XM_036154263.1 → XP_036010156.1  CLIP-associating protein 1 isoform X9

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 783
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  14. XM_030243449.2 → XP_030099309.1  CLIP-associating protein 1 isoform X10

    Conserved Domains (5) summary
    PHA03307
    Location:651 → 729
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam11179
    Location:572 → 772
    DUF2967; Protein of unknown function (DUF2967)
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  15. XM_006529948.2 → XP_006530011.1  CLIP-associating protein 1 isoform X30

    Conserved Domains (4) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam05956
    Location:662 → 804
    APC_basic; APC basic domain
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  16. XM_030243485.2 → XP_030099345.1  CLIP-associating protein 1 isoform X29

    Conserved Domains (4) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam05956
    Location:662 → 804
    APC_basic; APC basic domain
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  17. XM_036154278.1 → XP_036010171.1  CLIP-associating protein 1 isoform X21

    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  18. XM_011248108.2 → XP_011246410.1  CLIP-associating protein 1 isoform X22

    UniProtKB/TrEMBL
    A0A087WQF1
    Conserved Domains (4) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam11179
    Location:563 → 763
    DUF2967; Protein of unknown function (DUF2967)
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  19. XM_036154284.1 → XP_036010177.1  CLIP-associating protein 1 isoform X24

    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  20. XM_036154280.1 → XP_036010173.1  CLIP-associating protein 1 isoform X23

    Conserved Domains (4) summary
    PHA03307
    Location:649 → 721
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  21. XM_036154271.1 → XP_036010164.1  CLIP-associating protein 1 isoform X17

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 767
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  22. XM_011248107.2 → XP_011246409.1  CLIP-associating protein 1 isoform X13

    UniProtKB/TrEMBL
    E9QKH0
    Conserved Domains (4) summary
    PHA03307
    Location:564 → 767
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  23. XM_036154272.1 → XP_036010165.1  CLIP-associating protein 1 isoform X18

    Conserved Domains (4) summary
    PHA03307
    Location:572 → 713
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  24. XM_030243482.2 → XP_030099342.1  CLIP-associating protein 1 isoform X27

    Conserved Domains (4) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam05956
    Location:566 → 788
    APC_basic; APC basic domain
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  25. XM_036154292.1 → XP_036010185.1  CLIP-associating protein 1 isoform X28

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 808
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  26. XM_036154274.1 → XP_036010167.1  CLIP-associating protein 1 isoform X19

    Conserved Domains (4) summary
    PHA03307
    Location:564 → 799
    PHA03307; transcriptional regulator ICP4; Provisional
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  27. XM_036154275.1 → XP_036010168.1  CLIP-associating protein 1 isoform X20

    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  28. XM_036154286.1 → XP_036010179.1  CLIP-associating protein 1 isoform X25

    UniProtKB/TrEMBL
    J3QP81
    Related
    ENSMUSP00000137137.2, ENSMUST00000178710.8
    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

  29. XM_030243461.2 → XP_030099321.1  CLIP-associating protein 1 isoform X16

    Conserved Domains (4) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam05956
    Location:566 → 724
    APC_basic; APC basic domain
    pfam12348
    Location:326 → 537
    CLASP_N; CLASP N terminal

  30. XM_036154288.1 → XP_036010181.1  CLIP-associating protein 1 isoform X26

    Conserved Domains (3) summary
    sd00044
    Location:93 → 120
    HEAT; HEAT repeat [structural motif]
    pfam02985
    Location:168 → 198
    HEAT; HEAT repeat
    pfam12348
    Location:324 → 537
    CLASP_N; CLASP N terminal

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001081276.1: Suppressed sequence

    Description
    NM_001081276.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

  2. NM_177548.2: Suppressed sequence

    Description
    NM_177548.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80TV8.2 GenPept UniProtKB/Swiss-Prot:Q80TV8

Gene LinkOut

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