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Cpb1 carboxypeptidase B1 (tissue) [ Mus musculus (house mouse) ]

Gene ID: 76703, updated on 23-May-2018

Summary

Official Symbol
Cpb1provided by MGI
Official Full Name
carboxypeptidase B1 (tissue)provided by MGI
Primary source
MGI:MGI:1923953
See related
Ensembl:ENSMUSG00000011463 Vega:OTTMUSG00000024346
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI504870; 0910001A18Rik; 1810063F02Rik; 2210008M23Rik
Expression
Biased expression in small intestine adult (RPKM 332.2), spleen adult (RPKM 215.9) and 2 other tissues See more
Orthologs

Genomic context

See Cpb1 in Genome Data Viewer
Location:
3 A2; 3 6.29 cM
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (20249479..20275733, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (20149383..20174651, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene carboxypeptidase A3, mast cell Neighboring gene microRNA 7007 Neighboring gene predicted gene, 31320 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene predicted gene, 46797 Neighboring gene angiotensin II receptor, type 1b

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from BioSystems

  • Pancreatic secretion, organism-specific biosystem (from KEGG)
    Pancreatic secretion, organism-specific biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
  • Pancreatic secretion, conserved biosystem (from KEGG)
    Pancreatic secretion, conserved biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
  • Protein digestion and absorption, organism-specific biosystem (from KEGG)
    Protein digestion and absorption, organism-specific biosystemProtein is a dietary component essential for nutritional homeostasis in humans. Normally, ingested protein undergoes a complex series of degradative processes following the action of gastric, pancrea...
  • Protein digestion and absorption, conserved biosystem (from KEGG)
    Protein digestion and absorption, conserved biosystemProtein is a dietary component essential for nutritional homeostasis in humans. Normally, ingested protein undergoes a complex series of degradative processes following the action of gastric, pancrea...

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
carboxypeptidase activity ISO
Inferred from Sequence Orthology
more info
 
metallocarboxypeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteolysis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
carboxypeptidase B
NP_083982.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029706.2NP_083982.1  carboxypeptidase B precursor

    Status: VALIDATED

    Source sequence(s)
    AC158937, AK003061, AK008678, BQ831426
    Consensus CDS
    CCDS17263.1
    UniProtKB/TrEMBL
    B2RS76
    Related
    ENSMUSP00000011607.5, OTTMUSP00000029027, ENSMUST00000011607.5, OTTMUST00000059645
    Conserved Domains (2) summary
    cd03871
    Location:112411
    M14_CPB; Peptidase M14 carboxypeptidase subfamily A/B-like; Carboxypeptidase B subgroup
    pfam02244
    Location:27100
    Propep_M14; Carboxypeptidase activation peptide

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

    Range
    20249479..20275733 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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