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Paqr4 progestin and adipoQ receptor family member IV [ Mus musculus (house mouse) ]

Gene ID: 76498, updated on 19-Sep-2024

Summary

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Official Symbol
Paqr4provided by MGI
Official Full Name
progestin and adipoQ receptor family member IVprovided by MGI
Primary source
MGI:MGI:1923748
See related
Ensembl:ENSMUSG00000023909 AllianceGenome:MGI:1923748
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500004C10Rik
Summary
Predicted to enable signaling receptor activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including acetabular region; ganglia; inner ear; limb; and rib. Orthologous to human PAQR4 (progestin and adipoQ receptor family member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in colon adult (RPKM 104.3), large intestine adult (RPKM 48.5) and 21 other tissues See more
Orthologs
human all
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Genomic context

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Location:
17 A3.3; 17 12.02 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (23955160..23959873, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (23736186..23740899, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene claudin 9 Neighboring gene glycine rich extracellular protein 1 Neighboring gene protein kinase, membrane associated tyrosine/threonine 1 Neighboring gene kringle containing transmembrane protein 2 Neighboring gene RIKEN cDNA 9530082P21 gene Neighboring gene FLYWCH-type zinc finger 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. Tang YT, et al. J Mol Evol, 2005 Sep. PMID 16044242
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein stabilization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of ceramide biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
progestin and adipoQ receptor family member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023824.3 → NP_076313.1  progestin and adipoQ receptor family member 4

    See identical proteins and their annotated locations for NP_076313.1

    Status: PROVISIONAL

    Source sequence(s)
    AC122821
    Consensus CDS
    CCDS28461.1
    UniProtKB/Swiss-Prot
    Q3U7G1, Q9JJE4
    Related
    ENSMUSP00000024702.4, ENSMUST00000024702.5
    Conserved Domains (1) summary
    cl03831
    Location:43 → 254
    HlyIII; Haemolysin-III related

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    23955160..23959873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525098.3 → XP_006525161.1  progestin and adipoQ receptor family member 4 isoform X1

    Conserved Domains (1) summary
    cl03831
    Location:20 → 187
    HlyIII; Haemolysin-III related
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9JJE4.1 GenPept UniProtKB/Swiss-Prot:Q9JJE4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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