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Usp31 ubiquitin specific peptidase 31 [ Mus musculus (house mouse) ]

Gene ID: 76179, updated on 26-Sep-2022

Summary

Official Symbol
Usp31provided by MGI
Official Full Name
ubiquitin specific peptidase 31provided by MGI
Primary source
MGI:MGI:1923429
See related
Ensembl:ENSMUSG00000063317 AllianceGenome:MGI:1923429
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1203; 6330567E21Rik
Summary
Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Predicted to be located in nucleus. Orthologous to human USP31 (ubiquitin specific peptidase 31). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 6.5), cortex adult (RPKM 6.4) and 26 other tissues See more
Orthologs
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Genomic context

See Usp31 in Genome Data Viewer
Location:
7; 7 F2
Exon count:
16
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (121241244..121306683, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (121642021..121707461, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene heparan sulfate (glucosamine) 3-O-sulfotransferase 2 Neighboring gene RIKEN cDNA 4933432K03 gene Neighboring gene RIKEN cDNA 1700025J12 gene Neighboring gene sodium channel, nonvoltage-gated 1 gamma Neighboring gene predicted gene, 36848 Neighboring gene sodium channel, nonvoltage-gated 1 beta

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in protein deubiquitination ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ubiquitin carboxyl-terminal hydrolase 31
Names
ubiquitin specific protease 31
NP_001028345.1
XP_006508359.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033173.2NP_001028345.1  ubiquitin carboxyl-terminal hydrolase 31

    Status: VALIDATED

    Source sequence(s)
    AC134870
    Consensus CDS
    CCDS52386.1
    UniProtKB/TrEMBL
    A0A8C6ICQ0, E9Q6Y8
    Related
    ENSMUSP00000040037.7, ENSMUST00000046929.7
    Conserved Domains (2) summary
    cd02674
    Location:589756
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl02553
    Location:124329
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    121241244..121306683 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508296.5XP_006508359.1  ubiquitin carboxyl-terminal hydrolase 31 isoform X1

    Conserved Domains (1) summary
    COG5560
    Location:121664
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]