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Coa5 cytochrome C oxidase assembly factor 5 [ Mus musculus (house mouse) ]

Gene ID: 76178, updated on 30-Apr-2024

Summary

Official Symbol
Coa5provided by MGI
Official Full Name
cytochrome C oxidase assembly factor 5provided by MGI
Primary source
MGI:MGI:1923428
See related
Ensembl:ENSMUSG00000026112 AllianceGenome:MGI:1923428
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pet191; 1700001A24Rik; 6330578E17Rik
Summary
Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrion. Is expressed in heart ventricle; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 3. Orthologous to human COA5 (cytochrome c oxidase assembly factor 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 45.9), mammary gland adult (RPKM 36.6) and 28 other tissues See more
Orthologs
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Genomic context

See Coa5 in Genome Data Viewer
Location:
1 B; 1 15.46 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (37456166..37469184, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (37417085..37430103, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene cyclic nucleotide gated channel alpha 3 Neighboring gene STARR-positive B cell enhancer ABC_E788 Neighboring gene RIKEN cDNA 4930439A04 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:37374616-37374799 Neighboring gene inositol polyphosphate-4-phosphatase, type I Neighboring gene STARR-seq mESC enhancer starr_00675 Neighboring gene unc-50 homolog Neighboring gene mannoside acetylglucosaminyltransferase 4, isoenzyme A Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:37528102-37528303 Neighboring gene STARR-positive B cell enhancer ABC_E1540 Neighboring gene G1 to S phase transition pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 

General protein information

Preferred Names
cytochrome c oxidase assembly factor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198006.4NP_932123.3  cytochrome c oxidase assembly factor 5

    See identical proteins and their annotated locations for NP_932123.3

    Status: VALIDATED

    Source sequence(s)
    AA616104, AK166651, BQ176168, BY779699, CN531814
    Consensus CDS
    CCDS35541.1
    UniProtKB/Swiss-Prot
    Q99M07
    Related
    ENSMUSP00000027286.7, ENSMUST00000027286.7
    Conserved Domains (1) summary
    pfam10203
    Location:1171
    Pet191_N; Cytochrome c oxidase assembly protein PET191

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    37456166..37469184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)