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Zfp821 zinc finger protein 821 [ Mus musculus (house mouse) ]

Gene ID: 75871, updated on 2-Oct-2018

Summary

Official Symbol
Zfp821provided by MGI
Official Full Name
zinc finger protein 821provided by MGI
Primary source
MGI:MGI:1923121
See related
Ensembl:ENSMUSG00000031728 Vega:OTTMUSG00000061922
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf821; 4930566A11Rik
Expression
Broad expression in CNS E14 (RPKM 11.3), testis adult (RPKM 11.1) and 27 other tissues See more
Orthologs

Genomic context

See Zfp821 in Genome Data Viewer
Location:
8; 8 D3
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (109705494..109724932)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (112229449..112248832)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene dihydroorotate dehydrogenase Neighboring gene polycystic kidney disease 1 like 3 Neighboring gene increased sodium tolerance 1 homolog (yeast) Neighboring gene predicted gene, 39248 Neighboring gene ataxin 1-like Neighboring gene La ribonucleoprotein domain family, member 1B pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
transcription regulatory region DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167946.2NP_001161418.1  zinc finger protein 821 isoform a

    See identical proteins and their annotated locations for NP_001161418.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 5-8 all encode the same isoform (a).
    Source sequence(s)
    AC132138, AK136168, BC059844
    Consensus CDS
    CCDS40473.1
    UniProtKB/Swiss-Prot
    Q6PD05
    Related
    ENSMUSP00000034163.8, ENSMUST00000034163.8
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  2. NM_001286391.1NP_001273320.1  zinc finger protein 821 isoform b

    See identical proteins and their annotated locations for NP_001273320.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 3, 4, and 9-11 all encode the same isoform (b).
    Source sequence(s)
    AC132138, AK165387, BC059844
    Consensus CDS
    CCDS85609.1
    UniProtKB/TrEMBL
    A0A1D5RLE5
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  3. NM_001286393.1NP_001273322.1  zinc finger protein 821 isoform b

    See identical proteins and their annotated locations for NP_001273322.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon compared to variant 1. The resulting isoform (b) has a shorter N-terminus compared to isoform a. Variants 3, 4 and 9-11 all encode the same isoform (b).
    Source sequence(s)
    AC132138, AK136168, BC059844
    Consensus CDS
    CCDS85609.1
    UniProtKB/Swiss-Prot
    Q6PD05
    UniProtKB/TrEMBL
    A0A1D5RLE5
    Related
    ENSMUSP00000148334.1, OTTMUSP00000078367, ENSMUST00000212964.1, OTTMUST00000151118
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  4. NM_001363380.1NP_001350309.1  zinc finger protein 821 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 1, 2, and 6-8, encodes isoform a.
    Source sequence(s)
    AC132138, BC059014, CN714981, CN721180
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  5. NM_001363381.1NP_001350310.1  zinc finger protein 821 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variants 1, 2, 5, 7, and 8, encodes isoform a.
    Source sequence(s)
    AC132138, BC059014
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  6. NM_001363382.1NP_001350311.1  zinc finger protein 821 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 1, 2, 5, 6, and 8, encodes isoform a.
    Source sequence(s)
    AC132138, BC059014, CF173118
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  7. NM_001363383.1NP_001350312.1  zinc finger protein 821 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 1, 2, 5, 6, and 7, encodes isoform a
    Source sequence(s)
    AC132138
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  8. NM_001363384.1NP_001350313.1  zinc finger protein 821 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9), as well as variants 3, 4, 10, and 11, encodes isoform b.
    Source sequence(s)
    AC132138, BC059014, CN721180
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  9. NM_001363385.1NP_001350314.1  zinc finger protein 821 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC132138
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  10. NM_001363386.1NP_001350315.1  zinc finger protein 821 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), as well as variants 3, 4, 9, and 10, encodes isoform b.
    Source sequence(s)
    AC132138, BC059014, BM950913
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  11. NM_001363387.1NP_001350316.1  zinc finger protein 821 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC132138, BC059014, BM950913
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  12. NM_029468.3NP_083744.2  zinc finger protein 821 isoform a

    See identical proteins and their annotated locations for NP_083744.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1, 2, and 5-8 all encode the same isoform (a).
    Source sequence(s)
    BC059014, BC059844, BY240329
    Consensus CDS
    CCDS40473.1
    UniProtKB/Swiss-Prot
    Q6PD05
    Related
    ENSMUSP00000148348.1, OTTMUSP00000078369, ENSMUST00000212000.1, OTTMUST00000151120
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

    Range
    109705494..109724932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248534.2XP_011246836.1  zinc finger protein 821 isoform X1

    See identical proteins and their annotated locations for XP_011246836.1

    UniProtKB/Swiss-Prot
    Q6PD05
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  2. XM_011248536.2XP_011246838.1  zinc finger protein 821 isoform X1

    UniProtKB/Swiss-Prot
    Q6PD05
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  3. XM_006531468.2XP_006531531.1  zinc finger protein 821 isoform X2

    UniProtKB/TrEMBL
    A0A1D5RLE5
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  4. XM_017312997.1XP_017168486.1  zinc finger protein 821 isoform X1

    UniProtKB/Swiss-Prot
    Q6PD05
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  5. XM_017312999.1XP_017168488.1  zinc finger protein 821 isoform X2

    UniProtKB/TrEMBL
    A0A1D5RLE5
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  6. XM_017312998.1XP_017168487.1  zinc finger protein 821 isoform X2

    UniProtKB/TrEMBL
    A0A1D5RLE5
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
  7. XM_011248533.2XP_011246835.1  zinc finger protein 821 isoform X1

    UniProtKB/Swiss-Prot
    Q6PD05
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  8. XM_011248535.1XP_011246837.1  zinc finger protein 821 isoform X1

    UniProtKB/Swiss-Prot
    Q6PD05
    Conserved Domains (2) summary
    sd00017
    Location:121141
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl25887
    Location:276388
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  9. XM_011248537.1XP_011246839.1  zinc finger protein 821 isoform X2

    UniProtKB/TrEMBL
    A0A1D5RLE5
    Conserved Domains (3) summary
    sd00017
    Location:222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07946
    Location:143204
    DUF1682; Protein of unknown function (DUF1682)
    cl27170
    Location:92232
    DUF460; Protein of unknown function (DUF460)
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