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Saxo1 stabilizer of axonemal microtubules 1 [ Mus musculus (house mouse) ]

Gene ID: 75811, updated on 7-May-2024

Summary

Official Symbol
Saxo1provided by MGI
Official Full Name
stabilizer of axonemal microtubules 1provided by MGI
Primary source
MGI:MGI:1923061
See related
Ensembl:ENSMUSG00000028492 AllianceGenome:MGI:1923061
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam154a; 4930500O09Rik
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including cold acclimation; positive regulation of cilium assembly; and protein stabilization. Predicted to be located in motile cilium. Predicted to be active in microtubule cytoskeleton and sperm flagellum. Orthologous to human SAXO1 (stabilizer of axonemal microtubules 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 28.8) See more
Orthologs
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Genomic context

See Saxo1 in Genome Data Viewer
Location:
4 C4; 4 40.69 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (86362662..86476540, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (86444425..86558303, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene ADAMTS-like 1 Neighboring gene STARR-seq mESC enhancer starr_10687 Neighboring gene predicted gene, 25811 Neighboring gene STARR-seq mESC enhancer starr_10689 Neighboring gene STARR-seq mESC enhancer starr_10690 Neighboring gene STARR-seq mESC enhancer starr_10691 Neighboring gene STARR-seq mESC enhancer starr_10692 Neighboring gene predicted gene, 33730 Neighboring gene STARR-seq mESC enhancer starr_10693 Neighboring gene STARR-positive B cell enhancer mm9_chr4:86183948-86184249 Neighboring gene STARR-positive B cell enhancer ABC_E4635 Neighboring gene predicted gene, 26017 Neighboring gene stabilizer of axonemal microtubules 1, opposite strand Neighboring gene Ras-related GTP binding A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3)  1 citation
  • Targeted (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cellular response to cold ISO
Inferred from Sequence Orthology
more info
 
involved_in cold acclimation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cilium assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in axonemal microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in axonemal microtubule ISO
Inferred from Sequence Orthology
more info
 
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centriole ISO
Inferred from Sequence Orthology
more info
 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in motile cilium ISO
Inferred from Sequence Orthology
more info
 
is_active_in sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in sperm flagellum ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
stabilizer of axonemal microtubules 1
Names
family with sequence similarity 154, member A
likely ortholog of H. sapiens chromosome 9 open reading frame 138 (C9orf138)
stablizer of axonemal microtubules 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081096.1NP_001074565.1  stabilizer of axonemal microtubules 1

    See identical proteins and their annotated locations for NP_001074565.1

    Status: PROVISIONAL

    Source sequence(s)
    AL824705, AL824707
    Consensus CDS
    CCDS38795.1
    UniProtKB/TrEMBL
    B1AXP3
    Related
    ENSMUSP00000030216.6, ENSMUST00000030216.6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    86362662..86476540 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320434.1XP_017175923.1  stabilizer of axonemal microtubules 1 isoform X1

    Related
    ENSMUST00000151481.8