Cdyl2 chromodomain protein, Y chromosome-like 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cdyl2provided by MGI
Official Full Name: chromodomain protein, Y chromosome-like 2provided by MGI
Primary source: MGI:MGI:1923046
See related: Ensembl:ENSMUSG00000031758 AllianceGenome:MGI:1923046
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm20194; 1700029M19Rik; 4930453I21Rik
Summary: Enables methylated histone binding activity. Located in nucleus. Orthologous to human CDYL2 (chromodomain Y like 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in cerebellum adult (RPKM 1.6), thymus adult (RPKM 1.5) and 26 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8; 8 E1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (117295462..117459730, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (116568723..116732991, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH139825 (e-PCR)
- UniSTS:221909

D8Mit360 (e-PCR), detects polymorphism
- UniSTS:131578

Homology

Orthologs from Annotation Pipeline: 347 organisms have orthologs with human gene Cdyl2
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables methylated histone binding	IDA Inferred from Direct Assay more info	PubMed
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: chromodomain Y-like protein 2

Names: CDY-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_029441.3 → NP_083717.1 chromodomain Y-like protein 2

See identical proteins and their annotated locations for NP_083717.1

Status: VALIDATED

Source sequence(s)

AC112969, BC058956

Consensus CDS

CCDS40488.1

UniProtKB/Swiss-Prot

Q9D5D8

UniProtKB/TrEMBL

A0A6P5Q968

Related

ENSMUSP00000104730.3, ENSMUST00000109102.4

Conserved Domains (2) summary

cd06558
Location:249 → 445

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

cd18634
Location:6 → 57

CD_CDY; chromodomain of the Chromodomain Y-like protein family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000074.7 Reference GRCm39 C57BL/6J

Range

117295462..117459730 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017312996.3 → XP_017168485.1 chromodomain Y-like protein 2 isoform X1

Conserved Domains (1) summary

cd06558
Location:106 → 302

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...