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ZSCAN20 zinc finger and SCAN domain containing 20 [ Homo sapiens (human) ]

Gene ID: 7579, updated on 23-Nov-2021

Summary

Official Symbol
ZSCAN20provided by HGNC
Official Full Name
zinc finger and SCAN domain containing 20provided by HGNC
Primary source
HGNC:HGNC:13093
See related
Ensembl:ENSG00000121903 MIM:611315
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KOX29; ZNF31; ZFP-31; ZNF360
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See ZSCAN20 in Genome Data Viewer
Location:
1p35.1
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (33472591..33504253)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (33938246..33967243)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 11456 Neighboring gene proteasome 20S subunit alpha 3 pseudogene Neighboring gene toll like receptor 12, pseudogene Neighboring gene CUB and Sushi multiple domains 2 Neighboring gene uncharacterized LOC105378638

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger and SCAN domain-containing protein 20
Names
zinc finger protein 31
zinc finger protein 360
zinc finger protein KOX29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001377376.1NP_001364305.1  zinc finger and SCAN domain-containing protein 20 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC115285, AL138837
    Related
    ENSP00000507139.1, ENST00000684572.1
    Conserved Domains (4) summary
    COG5048
    Location:6991029
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:740760
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:47132
    SCAN; SCAN domain
    pfam13837
    Location:323404
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  2. NM_001377377.1NP_001364306.1  zinc finger and SCAN domain-containing protein 20 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC115285, AL138837
    Conserved Domains (4) summary
    COG5048
    Location:6981028
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:739759
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:47132
    SCAN; SCAN domain
    pfam13837
    Location:323404
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  3. NM_001377378.1NP_001364307.1  zinc finger and SCAN domain-containing protein 20 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC115285, AL138837
    Conserved Domains (4) summary
    COG5048
    Location:645975
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:686706
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:47132
    SCAN; SCAN domain
    pfam13837
    Location:269350
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  4. NM_001377379.1NP_001364308.1  zinc finger and SCAN domain-containing protein 20 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC115285, AL138837
    Conserved Domains (3) summary
    COG5048
    Location:381711
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:422442
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13837
    Location:586
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  5. NM_145238.6NP_660281.3  zinc finger and SCAN domain-containing protein 20 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC115285, AL138837
    Consensus CDS
    CCDS41300.1
    Related
    ENSP00000355053.3, ENST00000361328.7
    Conserved Domains (4) summary
    COG5048
    Location:6991029
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:740760
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:47132
    SCAN; SCAN domain
    pfam13837
    Location:323404
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    33472591..33504253
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017002239.1XP_016857728.1  zinc finger and SCAN domain-containing protein 20 isoform X4

    Conserved Domains (3) summary
    COG5048
    Location:381711
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:422442
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13837
    Location:586
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  2. XM_017002237.1XP_016857726.1  zinc finger and SCAN domain-containing protein 20 isoform X1

    UniProtKB/Swiss-Prot
    P17040
    Conserved Domains (4) summary
    COG5048
    Location:6991029
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:740760
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:47132
    SCAN; SCAN domain
    pfam13837
    Location:323404
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  3. XM_017002238.1XP_016857727.1  zinc finger and SCAN domain-containing protein 20 isoform X2

    UniProtKB/Swiss-Prot
    P17040
    Conserved Domains (4) summary
    COG5048
    Location:6981028
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:739759
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:47132
    SCAN; SCAN domain
    pfam13837
    Location:323404
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  4. XM_017002241.1XP_016857730.1  zinc finger and SCAN domain-containing protein 20 isoform X4

    Conserved Domains (3) summary
    COG5048
    Location:381711
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:422442
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13837
    Location:586
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
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