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Idnk idnK gluconokinase homolog (E. coli) [ Mus musculus (house mouse) ]

Gene ID: 75731, updated on 12-May-2024

Summary

Official Symbol
Idnkprovided by MGI
Official Full Name
idnK gluconokinase homolog (E. coli)provided by MGI
Primary source
MGI:MGI:1922981
See related
Ensembl:ENSMUSG00000050002 AllianceGenome:MGI:1922981
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5133401N09Rik
Summary
Predicted to enable gluconokinase activity. Predicted to be involved in D-gluconate catabolic process. Predicted to act upstream of or within phosphorylation. Is expressed in nervous system and thymus primordium. Orthologous to human IDNK (IDNK gluconokinase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 7.5), CNS E11.5 (RPKM 7.1) and 28 other tissues See more
Orthologs
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Genomic context

See Idnk in Genome Data Viewer
Location:
13 B1; 13 30.95 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (58305076..58315358)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (58157649..58164693)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40964 Neighboring gene RIKEN cDNA 1700066J03 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:58258990-58259099 Neighboring gene STARR-positive B cell enhancer ABC_E10797 Neighboring gene ubiquilin 1 Neighboring gene 60S ribosomal protein L17 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables gluconokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in D-gluconate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
probable gluconokinase
Names
gluconate kinase
NP_001041525.1
NP_932121.2
XP_036014105.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048060.2NP_001041525.1  probable gluconokinase isoform b

    See identical proteins and their annotated locations for NP_001041525.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a distinct and shorter C-terminus, compared to isoform a.
    Source sequence(s)
    AC163038, AK032811
    Consensus CDS
    CCDS36683.1
    UniProtKB/TrEMBL
    D3Z4J6
    Related
    ENSMUSP00000105494.3, ENSMUST00000109868.4
    Conserved Domains (1) summary
    cl17190
    Location:655
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  2. NM_198004.3NP_932121.2  probable gluconokinase isoform a

    See identical proteins and their annotated locations for NP_932121.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC163038, AK032811, AK045763, CX206109
    Consensus CDS
    CCDS36682.1
    UniProtKB/Swiss-Prot
    Q8R0J8
    Related
    ENSMUSP00000060218.8, ENSMUST00000051490.15
    Conserved Domains (2) summary
    COG0703
    Location:1184
    AroK; Shikimate kinase [Amino acid transport and metabolism]
    COG3265
    Location:10184
    GntK; Gluconate kinase [Carbohydrate transport and metabolism]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    58305076..58315358
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158212.1XP_036014105.1  probable gluconokinase isoform X1

    UniProtKB/TrEMBL
    D3Z4J6
    Conserved Domains (1) summary
    cl17190
    Location:655
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...