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ZNF24 zinc finger protein 24 [ Homo sapiens (human) ]

Gene ID: 7572, updated on 4-Jul-2021

Summary

Official Symbol
ZNF24provided by HGNC
Official Full Name
zinc finger protein 24provided by HGNC
Primary source
HGNC:HGNC:13032
See related
Ensembl:ENSG00000172466 MIM:194534
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KOX17; RSG-A; ZNF191; ZSCAN3; Zfp191
Expression
Ubiquitous expression in thyroid (RPKM 22.0), brain (RPKM 18.9) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF24 in Genome Data Viewer
Location:
18q12.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 18 NC_000018.10 (35332227..35344420, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (32912191..32924384, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 397 Neighboring gene zinc finger and SCAN domain containing 30 Neighboring gene zinc finger protein 271, pseudogene Neighboring gene uncharacterized LOC107985139 Neighboring gene zinc finger protein 396 Neighboring gene ribosomal protein L7a pseudogene 67

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in myelination ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
zinc finger protein 24
Names
retinoic acid suppression protein A
zinc finger and SCAN domain-containing protein 3
zinc finger protein 191
zinc finger protein 24 (KOX 17)
zinc finger protein KOX17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308123.2NP_001295052.1  zinc finger protein 24 isoform 2

    See identical proteins and their annotated locations for NP_001295052.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' and 3' structures compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC116447, AF542097, BG436261, CA314100
    Consensus CDS
    CCDS77175.1
    UniProtKB/Swiss-Prot
    P17028
    Related
    ENSP00000467655.1, ENST00000589881.5
    Conserved Domains (1) summary
    smart00431
    Location:48160
    SCAN; leucine rich region
  2. NM_001375815.1NP_001362744.1  zinc finger protein 24 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC116447
    Related
    ENSP00000382015.2, ENST00000399061.3
    Conserved Domains (3) summary
    smart00431
    Location:48160
    SCAN; leucine rich region
    COG5048
    Location:305358
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:253273
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_006965.4NP_008896.2  zinc finger protein 24 isoform 1

    See identical proteins and their annotated locations for NP_008896.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC116447
    Consensus CDS
    CCDS11912.1
    UniProtKB/Swiss-Prot
    P17028
    Related
    ENSP00000261332.5, ENST00000261332.11
    Conserved Domains (3) summary
    smart00431
    Location:48160
    SCAN; leucine rich region
    COG5048
    Location:305358
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:253273
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p13 Primary Assembly

    Range
    35332227..35344420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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