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Eif4b eukaryotic translation initiation factor 4B [ Mus musculus (house mouse) ]

Gene ID: 75705, updated on 17-Nov-2020

Summary

Official Symbol
Eif4bprovided by MGI
Official Full Name
eukaryotic translation initiation factor 4Bprovided by MGI
Primary source
MGI:MGI:95304
See related
Ensembl:ENSMUSG00000058655
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C85189; Eif4a2; AL024095; 2310046H11Rik
Expression
Ubiquitous expression in CNS E11.5 (RPKM 66.8), placenta adult (RPKM 58.0) and 28 other tissues See more
Orthologs

Genomic context

See Eif4b in Genome Data Viewer
Location:
15; 15 F2
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (101982208..102005608)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (102073773..102097173)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (101904204..101927604)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene keratin 18 Neighboring gene predicted gene, 41405 Neighboring gene uncharacterized LOC118568226 Neighboring gene tensin 2 Neighboring gene SPRY domain containing 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA strand annealing activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA strand-exchange activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
ribosomal small subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
eukaryotic translation initiation factor 4F complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
formation of translation preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
translation IEA
Inferred from Electronic Annotation
more info
 
translational initiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 4B
Names
eIF-4B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145625.3NP_663600.2  eukaryotic translation initiation factor 4B

    See identical proteins and their annotated locations for NP_663600.2

    Status: VALIDATED

    Source sequence(s)
    AK045250, CD563487, CO043713
    Consensus CDS
    CCDS49737.1
    UniProtKB/Swiss-Prot
    Q8BGD9
    Related
    ENSMUSP00000127774.1, ENSMUST00000169681.2
    Conserved Domains (3) summary
    COG0724
    Location:83256
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12402
    Location:95171
    RRM_eIF4B; RNA recognition motif in eukaryotic translation initiation factor 4B (eIF-4B) and similar proteins
    pfam08648
    Location:225290
    DUF1777; Protein of unknown function (DUF1777)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    101982208..102005608
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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