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ZNF17 zinc finger protein 17 [ Homo sapiens (human) ]

Gene ID: 7565, updated on 23-Nov-2021

Summary

Official Symbol
ZNF17provided by HGNC
Official Full Name
zinc finger protein 17provided by HGNC
Primary source
HGNC:HGNC:12958
See related
Ensembl:ENSG00000186272 MIM:619254
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HPF3; KOX10
Expression
Ubiquitous expression in thyroid (RPKM 2.0), ovary (RPKM 1.8) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF17 in Genome Data Viewer
Location:
19q13.43
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (57411161..57421934)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (57922529..57933302)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 2B Neighboring gene zinc finger protein 547 Neighboring gene zinc finger protein 548 Neighboring gene zinc finger protein 749 Neighboring gene vomeronasal 1 receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ40864, FLJ46058, FLJ46615, KIAA1947

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 17
Names
zinc finger protein 17 (HPF3, KOX 10)
zinc finger protein HPF3
zinc finger protein KOX10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330617.2NP_001317546.1  zinc finger protein 17 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC003002, AK127948, CK906092
    Consensus CDS
    CCDS82405.1
    UniProtKB/Swiss-Prot
    P17021
    Related
    ENSP00000302455.7, ENST00000307658.12
    Conserved Domains (4) summary
    COG5048
    Location:246658
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:222242
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1249
    KRAB; KRAB box
    pfam13465
    Location:487511
    zf-H2C2_2; Zinc-finger double domain
  2. NM_006959.3NP_008890.2  zinc finger protein 17 isoform 2

    See identical proteins and their annotated locations for NP_008890.2

    Status: VALIDATED

    Source sequence(s)
    AC003002, DA476988, DA746547
    Consensus CDS
    CCDS42636.1
    UniProtKB/Swiss-Prot
    P17021
    Related
    ENSP00000471905.1, ENST00000601808.1
    Conserved Domains (4) summary
    COG5048
    Location:244656
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:220240
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1047
    KRAB; KRAB box
    pfam13465
    Location:485509
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    57411161..57421934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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