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Tm4sf5 transmembrane 4 superfamily member 5 [ Mus musculus (house mouse) ]

Gene ID: 75604, updated on 5-Mar-2024


Official Symbol
Tm4sf5provided by MGI
Official Full Name
transmembrane 4 superfamily member 5provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000018919 AllianceGenome:MGI:1922854
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Predicted to enable arginine binding activity. Predicted to be involved in regulation of G1/S transition of mitotic cell cycle. Predicted to be located in lysosomal membrane and plasma membrane. Predicted to be integral component of membrane. Is expressed in gut; peritoneum; and urinary system. Orthologous to human TM4SF5 (transmembrane 4 L six family member 5). [provided by Alliance of Genome Resources, Apr 2022]
Biased expression in duodenum adult (RPKM 230.6), small intestine adult (RPKM 174.2) and 1 other tissue See more
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Genomic context

See Tm4sf5 in Genome Data Viewer
11 B3; 11 42.99 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (70396100..70402009)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (70505274..70511183)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:70265674-70265783 Neighboring gene mediator complex subunit 11 Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene zinc finger, MYND-type containing 15 Neighboring gene vitelline membrane outer layer 1 homolog (chicken) Neighboring gene glycolipid transfer protein domain containing 2

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


GeneRIFs: Gene References Into Functions

What's a GeneRIF?



Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables arginine binding ISO
Inferred from Sequence Orthology
more info
Process Evidence Code Pubs
involved_in regulation of G1/S transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
transmembrane 4 L6 family member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029360.3NP_083636.2  transmembrane 4 L6 family member 5

    See identical proteins and their annotated locations for NP_083636.2

    Status: VALIDATED

    Source sequence(s)
    AI323987, AK008064, BB798656, BB869909
    Consensus CDS
    Q91XF2, Q9D8G1
    ENSMUSP00000019063.3, ENSMUST00000019063.3
    Conserved Domains (1) summary
    L6_membrane; L6 membrane protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000077.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)