Hspb9 heat shock protein, alpha-crystallin-related, B9 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Hspb9provided by MGI
Official Full Name: heat shock protein, alpha-crystallin-related, B9provided by MGI
Primary source: MGI:MGI:1922732
See related: Ensembl:ENSMUSG00000017832 AllianceGenome:MGI:1922732
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1700007H20Rik
Summary: Predicted to be active in cytoplasm and nucleus. Orthologous to human HSPB9 (heat shock protein family B (small) member 9). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
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Genomic context

Location:: 11; 11 D

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (100604755..100605401)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (100713929..100714575)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Homology

Homologs of the Hspb9 gene: The Hspb9 gene is conserved in human, chimpanzee, dog, cow, and rat.
Orthologs from Annotation Pipeline: 196 organisms have orthologs with human gene Hspb9
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: heat shock protein beta-9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_029307.2 → NP_083583.2 heat shock protein beta-9

Status: VALIDATED

Source sequence(s)

AL591469

Consensus CDS

CCDS48932.2

UniProtKB/Swiss-Prot

A2A5F2

Related

ENSMUSP00000017976.3, ENSMUST00000017976.3

Conserved Domains (1) summary

cd06481
Location:50 → 135

ACD_HspB9_like; Alpha crystallin domain (ACD) found in mammalian small heat shock protein (sHsp) HspB9 and similar proteins. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers ...