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Etnk1 ethanolamine kinase 1 [ Mus musculus (house mouse) ]

Gene ID: 75320, updated on 26-Sep-2022

Summary

Official Symbol
Etnk1provided by MGI
Official Full Name
ethanolamine kinase 1provided by MGI
Primary source
MGI:MGI:1922570
See related
Ensembl:ENSMUSG00000030275 AllianceGenome:MGI:1922570
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EKI1; D6Ertd3e; 1110061E11Rik; 4930555L11Rik
Summary
Predicted to enable ethanolamine kinase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to act upstream of or within phospholipid biosynthetic process and phosphorylation. Predicted to be active in cytoplasm. Is expressed in several structures, including early embryo; endocrine gland; ganglia; hemolymphoid system; and retina. Orthologous to human ETNK1 (ethanolamine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in frontal lobe adult (RPKM 42.2), CNS E18 (RPKM 41.1) and 28 other tissues See more
Orthologs
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Genomic context

See Etnk1 in Genome Data Viewer
Location:
6 G3; 6 75.41 cM
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (143112592..143154272)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (143166866..143208546)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene C2 calcium-dependent domain containing 5 Neighboring gene predicted gene, 31108 Neighboring gene predicted gene, 38921 Neighboring gene uncharacterized LOC118567369 Neighboring gene RIKEN cDNA 1700126G02 gene Neighboring gene RIKEN cDNA 4930407I02 gene Neighboring gene predicted gene, 52926

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ethanolamine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ethanolamine kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphatidylethanolamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in phosphatidylethanolamine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ethanolamine kinase 1
Names
EKI 1
NP_083526.2
XP_006507074.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029250.2NP_083526.2  ethanolamine kinase 1

    See identical proteins and their annotated locations for NP_083526.2

    Status: VALIDATED

    Source sequence(s)
    AK044502, AK049691, BQ175711
    Consensus CDS
    CCDS57468.1
    UniProtKB/Swiss-Prot
    Q8BXQ0, Q9D4V0
    UniProtKB/TrEMBL
    A0A8C6HSA0
    Related
    ENSMUSP00000032413.5, ENSMUST00000032413.7
    Conserved Domains (2) summary
    PLN02236
    Location:26356
    PLN02236; choline kinase
    cd05157
    Location:49351
    ETNK_euk; Euykaryotic Ethanolamine kinase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    143112592..143154272
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507011.5XP_006507074.1  ethanolamine kinase 1 isoform X1

    Conserved Domains (1) summary
    cd05157
    Location:49261
    ETNK_euk; Euykaryotic Ethanolamine kinase

RNA

  1. XR_004933629.1 RNA Sequence

  2. XR_004933630.1 RNA Sequence