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Ccdc146 coiled-coil domain containing 146 [ Mus musculus (house mouse) ]

Gene ID: 75172, updated on 26-Sep-2022

Summary

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Official Symbol
Ccdc146provided by MGI
Official Full Name
coiled-coil domain containing 146provided by MGI
Primary source
MGI:MGI:1922422
See related
Ensembl:ENSMUSG00000064280 AllianceGenome:MGI:1922422
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1505; 4930528G09Rik
Summary
Predicted to be located in centriole. Predicted to be active in cytoskeleton. Orthologous to human CCDC146 (coiled-coil domain containing 146). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 5.6), ovary adult (RPKM 0.5) and 1 other tissue See more
Orthologs
human all
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Genomic context

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See Ccdc146 in Genome Data Viewer
Location:
5; 5 A3
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (21496749..21629675, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (21292422..21424677, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene neuroepithelial cell transforming gene 1 pseudogene Neighboring gene predicted gene, 42222 Neighboring gene gamma-secretase activating protein Neighboring gene VISTA enhancer mm186 Neighboring gene predicted gene, 50626 Neighboring gene fibrinogen-like protein 2 Neighboring gene family with sequence similarity 185, member A Neighboring gene F-box and leucine-rich repeat protein 13 Neighboring gene leucine rich repeat containing 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Clone Names

  • KIAA1505

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in centriole ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 

General protein information

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Preferred Names
coiled-coil domain-containing protein 146

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029195.1 → NP_083471.1  coiled-coil domain-containing protein 146

    Status: VALIDATED

    Source sequence(s)
    AC113052, AK015926, AK220398, AU018841
    Consensus CDS
    CCDS51427.1
    UniProtKB/TrEMBL
    E9Q9F7, Q5DTX2, Q9D511
    Related
    ENSMUSP00000110900.2, ENSMUST00000115245.8
    Conserved Domains (1) summary
    COG1196
    Location:150 → 920
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    21496749..21629675 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165573.1 → XP_036021466.1  coiled-coil domain-containing protein 146 isoform X1

    Conserved Domains (2) summary
    TIGR02168
    Location:15 → 349
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    NF033930
    Location:247 → 551
    pneumo_PspA; pneumococcal surface protein A

  2. XM_017321126.3 → XP_017176615.1  coiled-coil domain-containing protein 146 isoform X2

    Conserved Domains (1) summary
    TIGR02168
    Location:56 → 381
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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