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Rasd2 RASD family, member 2 [ Mus musculus (house mouse) ]

Gene ID: 75141, updated on 19-Jun-2024

Summary

Official Symbol
Rasd2provided by MGI
Official Full Name
RASD family, member 2provided by MGI
Primary source
MGI:MGI:1922391
See related
Ensembl:ENSMUSG00000034472 AllianceGenome:MGI:1922391
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rhes; TEM2; TEM-2; 4930526B11Rik
Summary
Predicted to enable several functions, including G-protein beta-subunit binding activity; GTP binding activity; and ubiquitin conjugating enzyme binding activity. Involved in dopaminergic synaptic transmission and locomotory behavior. Predicted to be located in plasma membrane. Orthologous to human RASD2 (RASD family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cortex adult (RPKM 15.5), frontal lobe adult (RPKM 12.6) and 18 other tissues See more
Orthologs
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Genomic context

See Rasd2 in Genome Data Viewer
Location:
8 C1; 8 35.61 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (75940572..75950741)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (75213944..75224113)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8248 Neighboring gene STARR-positive B cell enhancer ABC_E244 Neighboring gene heme oxygenase 1 Neighboring gene minichromosome maintenance complex component 5 Neighboring gene STARR-seq mESC enhancer starr_21928 Neighboring gene STARR-seq mESC enhancer starr_21930 Neighboring gene STARR-seq mESC enhancer starr_21931 Neighboring gene predicted gene 9644 Neighboring gene STARR-seq mESC enhancer starr_21933 Neighboring gene uridine monophosphate kinase, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G-protein beta-subunit binding ISO
Inferred from Sequence Orthology
more info
 
enables GTP binding ISO
Inferred from Sequence Orthology
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol 3-kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin conjugating enzyme binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
GTP-binding protein Rhes
Names
ras homolog enriched in striatum
NP_083458.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029182.2NP_083458.1  GTP-binding protein Rhes

    See identical proteins and their annotated locations for NP_083458.1

    Status: VALIDATED

    Source sequence(s)
    AC076974
    Consensus CDS
    CCDS52602.1
    UniProtKB/Swiss-Prot
    P63032, Q9WVD3
    UniProtKB/TrEMBL
    Q8JZW1
    Related
    ENSMUSP00000118070.2, ENSMUST00000139848.8
    Conserved Domains (1) summary
    cd04143
    Location:20266
    Rhes_like; Ras homolog enriched in striatum (Rhes) and activator of G-protein signaling 1 (Dexras1/AGS1)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    75940572..75950741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)