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epor erythropoietin receptor [ Danio rerio (zebrafish) ]

Gene ID: 751109, updated on 12-Aug-2018

Summary

Official Symbol
eporprovided by ZNC
Official Full Name
erythropoietin receptorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-071116-1
See related
Ensembl:ENSDARG00000090834
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Orthologs

Genomic context

See epor in Genome Data Viewer
Location:
chromosome: 3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (14544027..14561045)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (14394227..14411245)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 205 Neighboring gene RAB3D, member RAS oncogene family, b Neighboring gene SWIM-type zinc finger 7 associated protein 1 Neighboring gene zinc finger protein 653

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • EPO Receptor Signaling, organism-specific biosystem (from WikiPathways)
    EPO Receptor Signaling, organism-specific biosystemThe erythropoietin receptor is a 66 kDa peptide and is a member of the cytokine receptor family. The receptor is tyrosine phosphorylated upon binding by erythropoietin and associates with and activat...
  • Kit Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Kit Receptor Signaling Pathway, organism-specific biosystemKit is a receptor protein tyrosine kinase, which is a receptor for stem cell factor or kit ligand. Signaling through Kit is important for formation of red cells, lymphocytes, mast cells and platelets...

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
pronephros development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
erythropoietin receptor
Names
type I single-transmembrane cytokine receptor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001043334.1NP_001036799.1  erythropoietin receptor precursor

    See identical proteins and their annotated locations for NP_001036799.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ273166
    UniProtKB/TrEMBL
    Q2VBQ8
    Related
    ENSDARP00000137905.1, ENSDART00000161710.2
    Conserved Domains (2) summary
    cd00063
    Location:136232
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09067
    Location:29130
    EpoR_lig-bind; Erythropoietin receptor, ligand binding

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    14544027..14561045
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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