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Ccdc181 coiled-coil domain containing 181 [ Mus musculus (house mouse) ]

Gene ID: 74895, updated on 30-Apr-2024

Summary

Official Symbol
Ccdc181provided by MGI
Official Full Name
coiled-coil domain containing 181provided by MGI
Primary source
MGI:MGI:1922145
See related
Ensembl:ENSMUSG00000026578 AllianceGenome:MGI:1922145
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930455F23Rik
Summary
Enables microtubule binding activity. Located in manchette and sperm flagellum. Is expressed in 3rd ventricle; 4th ventricle; and choroid invagination. Orthologous to human CCDC181 (coiled-coil domain containing 181). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 47.2), frontal lobe adult (RPKM 5.5) and 8 other tissues See more
Orthologs
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Genomic context

See Ccdc181 in Genome Data Viewer
Location:
1 H2.2; 1 71.59 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (164103126..164115416)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (164275598..164287847)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene coagulation factor V Neighboring gene microRNA 12178 Neighboring gene STARR-seq mESC enhancer starr_02865 Neighboring gene STARR-seq mESC enhancer starr_02866 Neighboring gene solute carrier family 19 (thiamine transporter), member 2 Neighboring gene STARR-seq mESC enhancer starr_02867 Neighboring gene STARR-positive B cell enhancer ABC_E797 Neighboring gene basic leucine zipper nuclear factor 1 Neighboring gene NME/NM23 family member 7 Neighboring gene STARR-positive B cell enhancer ABC_E5840 Neighboring gene STARR-seq mESC enhancer starr_02870 Neighboring gene predicted gene, 39690

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in manchette IDA
Inferred from Direct Assay
more info
PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 
located_in sperm flagellum IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
coiled-coil domain-containing protein 181

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029115.3NP_083391.2  coiled-coil domain-containing protein 181

    See identical proteins and their annotated locations for NP_083391.2

    Status: VALIDATED

    Source sequence(s)
    BC048086, BC060044
    Consensus CDS
    CCDS15434.1
    UniProtKB/Swiss-Prot
    Q3UF07, Q80ZU5, Q8C631, Q9CUL9
    Related
    ENSMUSP00000027867.7, ENSMUST00000027867.7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    164103126..164115416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154044.1XP_036009937.1  coiled-coil domain-containing protein 181 isoform X1

    Conserved Domains (1) summary
    pfam17380
    Location:298455
    DUF5401; Family of unknown function (DUF5401)