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Rab3il1 RAB3A interacting protein (rabin3)-like 1 [ Mus musculus (house mouse) ]

Gene ID: 74760, updated on 8-Nov-2022

Summary

Official Symbol
Rab3il1provided by MGI
Official Full Name
RAB3A interacting protein (rabin3)-like 1provided by MGI
Primary source
MGI:MGI:1922010
See related
Ensembl:ENSMUSG00000024663 AllianceGenome:MGI:1922010
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rab3ail1; 1200014K04Rik
Summary
Predicted to enable guanyl-nucleotide exchange factor activity; identical protein binding activity; and kinase binding activity. Predicted to be involved in exocytosis. Predicted to act upstream of or within protein transport. Predicted to be active in Golgi to plasma membrane transport vesicle. Is expressed in embryo. Orthologous to human RAB3IL1 (RAB3A interacting protein like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 100.1), liver E14.5 (RPKM 29.4) and 10 other tissues See more
Orthologs
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Genomic context

See Rab3il1 in Genome Data Viewer
Location:
19; 19 A
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (9979033..10015744)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10001669..10038380)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene ferritin heavy polypeptide 1 Neighboring gene bestrophin 1 Neighboring gene fatty acid desaturase 3 Neighboring gene predicted gene, 29917 Neighboring gene fatty acid desaturase 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi to plasma membrane transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
guanine nucleotide exchange factor for Rab-3A
Names
guanine nucleotide exchange factor for Rab3A
rab-3A-interacting-like protein 1
rab3A-interacting-like protein 1
rabin3-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347429.1NP_001334358.1  guanine nucleotide exchange factor for Rab-3A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC134437, AK161298
    Consensus CDS
    CCDS84417.1
    UniProtKB/Swiss-Prot
    Q8VDV3
    Related
    ENSMUSP00000113828.2, ENSMUST00000121418.8
    Conserved Domains (2) summary
    pfam06428
    Location:2391
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:148310
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  2. NM_001347430.1NP_001334359.1  guanine nucleotide exchange factor for Rab-3A isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC134437, AK004767
    Consensus CDS
    CCDS84416.1
    UniProtKB/TrEMBL
    A0A8C6I6J0, D3Z585
    Related
    ENSMUSP00000113551.2, ENSMUST00000117641.8
  3. NM_001378857.1NP_001365786.1  guanine nucleotide exchange factor for Rab-3A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC134437
    Conserved Domains (2) summary
    pfam06428
    Location:2391
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:148310
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  4. NM_001378858.1NP_001365787.1  guanine nucleotide exchange factor for Rab-3A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC134437
    Conserved Domains (2) summary
    pfam06428
    Location:2391
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:148310
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  5. NM_001378859.1NP_001365788.1  guanine nucleotide exchange factor for Rab-3A isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC134437
    UniProtKB/TrEMBL
    A0A571BDP7
    Related
    ENSMUSP00000158807.2, ENSMUST00000238672.2
    Conserved Domains (2) summary
    pfam06428
    Location:92160
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:267428
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  6. NM_001378860.1NP_001365789.1  guanine nucleotide exchange factor for Rab-3A isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC134437
    Conserved Domains (2) summary
    pfam06428
    Location:139190
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:194353
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  7. NM_001378861.1NP_001365790.1  guanine nucleotide exchange factor for Rab-3A isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC134437
    Conserved Domains (2) summary
    pfam06428
    Location:2373
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:78237
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  8. NM_144538.3NP_653121.1  guanine nucleotide exchange factor for Rab-3A isoform 1

    See identical proteins and their annotated locations for NP_653121.1

    Status: VALIDATED

    Source sequence(s)
    AC134437, AK161298, BB733894
    Consensus CDS
    CCDS29569.1
    UniProtKB/Swiss-Prot
    Q3TTM0, Q8VDV3
    Related
    ENSMUSP00000108786.3, ENSMUST00000113161.10
    Conserved Domains (1) summary
    pfam06428
    Location:92160
    Sec2p; GDP/GTP exchange factor Sec2p

RNA

  1. NR_153790.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC134437
  2. NR_166144.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC134437

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    9979033..10015744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161717.1XP_036017610.1  guanine nucleotide exchange factor for Rab-3A isoform X6

    Conserved Domains (2) summary
    pfam06428
    Location:139190
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:194353
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  2. XM_030251119.1XP_030106979.1  guanine nucleotide exchange factor for Rab-3A isoform X5

    Conserved Domains (1) summary
    pfam06428
    Location:2391
    Sec2p; GDP/GTP exchange factor Sec2p
  3. XM_030251123.1XP_030106983.1  guanine nucleotide exchange factor for Rab-3A isoform X7

    Conserved Domains (2) summary
    pfam06428
    Location:2391
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:148310
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  4. XM_006527414.1XP_006527477.1  guanine nucleotide exchange factor for Rab-3A isoform X2

    Conserved Domains (2) summary
    pfam06428
    Location:98166
    Sec2p; GDP/GTP exchange factor Sec2p
    pfam16046
    Location:30164
    FAM76; FAM76 protein
  5. XM_036161716.1XP_036017609.1  guanine nucleotide exchange factor for Rab-3A isoform X4

    Conserved Domains (2) summary
    pfam06428
    Location:98166
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:223385
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  6. XM_030251120.2XP_030106980.1  guanine nucleotide exchange factor for Rab-3A isoform X5

    Conserved Domains (1) summary
    pfam06428
    Location:2391
    Sec2p; GDP/GTP exchange factor Sec2p
  7. XM_006527412.1XP_006527475.1  guanine nucleotide exchange factor for Rab-3A isoform X1

    Conserved Domains (2) summary
    pfam06428
    Location:139207
    Sec2p; GDP/GTP exchange factor Sec2p
    pfam16046
    Location:71205
    FAM76; FAM76 protein
  8. XM_036161715.1XP_036017608.1  guanine nucleotide exchange factor for Rab-3A isoform X3

    UniProtKB/TrEMBL
    D3YZ86
    Related
    ENSMUSP00000120401.3, ENSMUST00000149967.9
    Conserved Domains (2) summary
    pfam06428
    Location:139207
    Sec2p; GDP/GTP exchange factor Sec2p
    cl41767
    Location:264426
    Rab11BD_RAB3IP_like; Rab11 binding domain of Rab-3A-interacting protein (RAB3IP), Rab-3A-interacting-like protein 1 (RAB3IL1) and similar proteins
  9. XM_011247385.4XP_011245687.1  guanine nucleotide exchange factor for Rab-3A isoform X5

    Conserved Domains (1) summary
    pfam06428
    Location:2391
    Sec2p; GDP/GTP exchange factor Sec2p

RNA

  1. XR_877692.3 RNA Sequence