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AR androgen receptor [ Pan troglodytes (chimpanzee) ]

Gene ID: 747460, updated on 20-Apr-2019

Summary

Gene symbol
AR
Gene description
androgen receptor
Locus tag
CK820_G0033181
See related
Ensembl:ENSPTRG00000032525
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs

Genomic context

Location:
chromosome: X
Exon count:
10
Annotation release Status Assembly Chr Location
105 current Clint_PTRv2 (GCF_002880755.1) X NC_036902.1 (62859039..63049352)
104 previous assembly Pan_tro 3.0 (GCF_000001515.7) X NC_006491.4 (66683002..66881102)
103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) X NC_006491.3 (67322147..67409527)

Chromosome X - NC_036902.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene polyadenylate-binding protein 2 pseudogene Neighboring gene polycomb complex protein BMI-1 pseudogene Neighboring gene protein argonaute-3-like

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Androgen receptor signaling pathway, organism-specific biosystem (from WikiPathways)
    Androgen receptor signaling pathway, organism-specific biosystemAndrogens, mainly testosterone and 5alpha-dihydrotestosterone (DHT) play significant role in the growth and development of the male reproductive organs. These steroid hormones bring about their biolo...
  • Nuclear Receptors, organism-specific biosystem (from WikiPathways)
    Nuclear Receptors, organism-specific biosystemNuclear receptors are a class of proteins found within the interior of cells that are responsible for sensing the presence of steroid and thyroid hormones and certain other molecules. In response, th...
  • Oocyte meiosis, organism-specific biosystem (from KEGG)
    Oocyte meiosis, organism-specific biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
  • Oocyte meiosis, conserved biosystem (from KEGG)
    Oocyte meiosis, conserved biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
  • Pathways in cancer, organism-specific biosystem (from KEGG)
    Pathways in cancer, organism-specific biosystem
    Pathways in cancer
  • Prostate cancer, organism-specific biosystem (from KEGG)
    Prostate cancer, organism-specific biosystemProstate cancer constitutes a major health problem in Western countries. It is the most frequently diagnosed cancer among men and the second leading cause of male cancer deaths. The identification of...
  • Prostate cancer, conserved biosystem (from KEGG)
    Prostate cancer, conserved biosystemProstate cancer constitutes a major health problem in Western countries. It is the most frequently diagnosed cancer among men and the second leading cause of male cancer deaths. The identification of...

General gene information

Markers

Homology

General protein information

Preferred Names
androgen receptor
Names
androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
dihydrotestosterone receptor
nuclear receptor subfamily 3 group C member 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009012.1NP_001009012.1  androgen receptor

    See identical proteins and their annotated locations for NP_001009012.1

    Status: PROVISIONAL

    Source sequence(s)
    U94177
    UniProtKB/Swiss-Prot
    O97775
    Related
    ENSPTRP00000076864.1, ENSPTRT00000086173.1
    Conserved Domains (3) summary
    cd07073
    Location:664909
    NR_LBD_AR; Ligand binding domain of the nuclear receptor androgen receptor, ligand activated transcription regulator
    cd07173
    Location:546627
    NR_DBD_AR; DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers
    pfam02166
    Location:6446
    Androgen_recep; Androgen receptor

RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Clint_PTRv2 Primary Assembly

Genomic

  1. NC_036902.1 Reference Clint_PTRv2 Primary Assembly

    Range
    62859039..63049352
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024352970.1XP_024208738.1  androgen receptor isoform X2

    Conserved Domains (2) summary
    cd07173
    Location:548622
    NR_DBD_AR; DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers
    pfam02166
    Location:6446
    Androgen_recep; Androgen receptor
  2. XM_016942685.2XP_016798174.1  androgen receptor isoform X1

    Related
    ENSPTRP00000083156.1
    Conserved Domains (2) summary
    cd07073
    Location:141386
    NR_LBD_AR; Ligand binding domain of the nuclear receptor androgen receptor, ligand activated transcription regulator
    cd07173
    Location:23104
    NR_DBD_AR; DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers

RNA

  1. XR_002941296.1 RNA Sequence

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