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Scrn3 secernin 3 [ Mus musculus (house mouse) ]

Gene ID: 74616, updated on 31-Jan-2019

Summary

Official Symbol
Scrn3provided by MGI
Official Full Name
secernin 3provided by MGI
Primary source
MGI:MGI:1921866
See related
Ensembl:ENSMUSG00000008226
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ses3; AI427019; AV002033; 4833415E20Rik
Expression
Ubiquitous expression in liver E14 (RPKM 6.8), liver E14.5 (RPKM 6.1) and 25 other tissues See more
Orthologs

Genomic context

See Scrn3 in Genome Data Viewer
Location:
2; 2 C3
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (73312652..73337818)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (73150709..73175864)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene trans-acting transcription factor 9 Neighboring gene corepressor interacting with RBPJ, 1 Neighboring gene G protein-coupled receptor 155 Neighboring gene predicted gene 13709 Neighboring gene predicted gene 13707

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
dipeptidase activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteolysis IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355711.1NP_001342640.1  secernin-3 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK050521, BY203757, BY695942
    Conserved Domains (1) summary
    cl00467
    Location:5178
    Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...
  2. NM_029022.1NP_083298.1  secernin-3 isoform 1

    See identical proteins and their annotated locations for NP_083298.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK014701, AK028703, AV002033, BE945683, BY203757
    Consensus CDS
    CCDS16128.1
    UniProtKB/Swiss-Prot
    Q3TMH2
    Related
    ENSMUSP00000088320.4, ENSMUST00000090811.10
    Conserved Domains (1) summary
    cl00467
    Location:5224
    Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

    Range
    73312652..73337818
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500313.3XP_006500376.1  secernin-3 isoform X1

    Conserved Domains (1) summary
    cl00467
    Location:28247
    Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...
  2. XM_006500314.2XP_006500377.1  secernin-3 isoform X2

    See identical proteins and their annotated locations for XP_006500377.1

    UniProtKB/Swiss-Prot
    Q3TMH2
    Conserved Domains (1) summary
    cl00467
    Location:5224
    Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...
  3. XM_011239820.2XP_011238122.1  secernin-3 isoform X3

RNA

  1. XR_866344.2 RNA Sequence

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