Format

Send to:

Choose Destination

LRRK2 leucine rich repeat kinase 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 745893, updated on 1-May-2017
Official Symbol
LRRK2provided by VGNC
Official Full Name
leucine rich repeat kinase 2provided by VGNC
Primary source
VGNC:VGNC:13210
See related
Ensembl:ENSPTRG00000004828
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
Location:
chromosome: 12
Exon count:
51
Annotation release Status Assembly Chr Location
104 current Pan_tro 3.0 (GCF_000001515.7) 12 NC_006479.4 (49767560..49911855, complement)
103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 12 NC_006479.3 (49080625..49225230, complement)

Chromosome 12 - NC_006479.4Genomic Context describing neighboring genes Neighboring gene mucin 19, oligomeric Neighboring gene microRNA 1244-3 Neighboring gene uncharacterized LOC107967539 Neighboring gene 60S ribosomal protein L30-like Neighboring gene solute carrier family 2 member 13

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Parkinson's disease, organism-specific biosystem (from KEGG)
    Parkinson's disease, organism-specific biosystemParkinson's disease (PD) is a progressive neurodegenerative movement disorder that results primarily from the death of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Mutations...

Markers

Homology

Preferred Names
leucine-rich repeat serine/threonine-protein kinase 2
XP_001168494.1
XP_009423870.1
XP_016779129.1

RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pan_tro 3.0 Primary Assembly

Genomic

  1. NC_006479.4 Reference Pan_tro 3.0 Primary Assembly

    Range
    49767560..49911855 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001168494.3XP_001168494.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X1

    See identical proteins and their annotated locations for XP_001168494.1

    UniProtKB/TrEMBL
    H2Q5Q4
    Related
    ENSPTRP00000008254
    Conserved Domains (6) summary
    cd09914
    Location:13341507
    RocCOR; Ras of complex proteins (Roc) C-terminal of Roc (COR) domain family
    smart00220
    Location:18842128
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG4886
    Location:10121307
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14068
    Location:18842135
    STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
    sd00033
    Location:10131036
    LRR_RI; leucine-rich repeat [structural motif]
    pfam16095
    Location:15271740
    COR; C-terminal of Roc, COR, domain
  2. XM_016923640.1XP_016779129.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X2

  3. XM_009425595.2XP_009423870.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X3

    Conserved Domains (7) summary
    cd09914
    Location:13341507
    RocCOR; Ras of complex proteins (Roc) C-terminal of Roc (COR) domain family
    smart00220
    Location:18842068
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG4886
    Location:10121307
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd00116
    Location:9861208
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:10131036
    LRR_RI; leucine-rich repeat [structural motif]
    pfam16095
    Location:15271740
    COR; C-terminal of Roc, COR, domain
    cl21453
    Location:18842093
    PKc_like; Protein Kinases, catalytic domain
Support Center