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Kcnk16 potassium channel, subfamily K, member 16 [ Mus musculus (house mouse) ]

Gene ID: 74571, updated on 18-Sep-2024

Summary

Official Symbol
Kcnk16provided by MGI
Official Full Name
potassium channel, subfamily K, member 16provided by MGI
Primary source
MGI:MGI:1921821
See related
Ensembl:ENSMUSG00000023387 AllianceGenome:MGI:1921821
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TALK1; TALK-1; 4731413G05Rik
Summary
Predicted to enable potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to act upstream of or within potassium ion transport. Predicted to be integral component of plasma membrane. Orthologous to human KCNK16 (potassium two pore domain channel subfamily K member 16). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in placenta adult (RPKM 5.7), liver E14.5 (RPKM 4.8) and 8 other tissues See more
Orthologs
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Genomic context

See Kcnk16 in Genome Data Viewer
Location:
14 A3; 14 11.49 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (20311443..20319337, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (20261375..20269269, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_36106 Neighboring gene predicted gene, 53834 Neighboring gene potassium channel, subfamily K, member 17 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1470 Neighboring gene nudix hydrolase 13 Neighboring gene ecdysoneless cell cycle regulator Neighboring gene STARR-seq mESC enhancer starr_36108 Neighboring gene STARR-positive B cell enhancer ABC_E7295

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables outward rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables potassium channel activity ISO
Inferred from Sequence Orthology
more info
 
enables potassium ion leak channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within potassium ion transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
potassium channel, subfamily K, member 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029006.2NP_083282.1  potassium channel, subfamily K, member 16

    See identical proteins and their annotated locations for NP_083282.1

    Status: VALIDATED

    Source sequence(s)
    AC159106
    Consensus CDS
    CCDS49407.1
    UniProtKB/TrEMBL
    G5E845
    Related
    ENSMUSP00000024155.8, ENSMUST00000024155.9
    Conserved Domains (1) summary
    pfam07885
    Location:92148
    Ion_trans_2; Ion channel

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    20311443..20319337 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)