U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MYRF myelin regulatory factor [ Homo sapiens (human) ]

Gene ID: 745, updated on 6-Jan-2026
Official Symbol
MYRFprovided by HGNC
Official Full Name
myelin regulatory factorprovided by HGNC
Primary source
HGNC:HGNC:1181
See related
Ensembl:ENSG00000124920 MIM:608329; AllianceGenome:HGNC:1181
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MRF; CUGS; NNO1; MMERV; Ndt80; 11orf9; pqn-47; C11orf9
Summary
This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Expression
Biased expression in stomach (RPKM 32.1), brain (RPKM 26.8) and 11 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See MYRF in Genome Data Viewer
Location:
11q12.2
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (61752636..61788518)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (61741556..61777435)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (61520108..61555990)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61393636-61394198 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61394199-61394759 Neighboring gene ribosomal protein lateral stalk subunit P0 pseudogene 2 Neighboring gene Sharpr-MPRA regulatory region 3465 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61396115-61397096 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61406067-61406567 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:61406607-61407134 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:61408188-61408713 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:61430561-61431253 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61450060-61450734 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61450735-61451408 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61457781-61458312 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61458313-61458844 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61462250-61462775 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61462776-61463302 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61463303-61463829 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61465411-61465936 Neighboring gene diacylglycerol lipase alpha Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61465937-61466463 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61466990-61467516 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61467517-61468042 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61468570-61469095 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61482486-61483272 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61483273-61484058 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61484845-61485630 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61485631-61486417 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61486418-61487203 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61487991-61488775 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61507907-61508480 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61514637-61515498 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61516359-61517220 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3397 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3398 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:61523524-61524723 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61524877-61525520 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61528511-61529267 Neighboring gene MYRF antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61535574-61536150 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61536151-61536726 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4800 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61546818-61547486 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61548157-61548825 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61552558-61553302 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61553303-61554047 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancers GRCh37_chr11:61559319-61560296 and GRCh37_chr11:61560297-61561272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61562818-61563318 Neighboring gene transmembrane protein 258 Neighboring gene microRNA 611 Neighboring gene flap structure-specific endonuclease 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Myelin regulatory factor drives remyelination in multiple sclerosis. Duncan GJ, et al. Acta Neuropathol, 2017 Sep. PMID 28631093
  2. Review of the phenotypic spectrum associated with haploinsufficiency of MYRF. Rossetti LZ, et al. Am J Med Genet A, 2019 Jul. PMID 31069960, Free PMC Article
  3. MYRF haploinsufficiency causes 46,XY and 46,XX disorders of sex development: bioinformatics consideration. Hamanaka K, et al. Hum Mol Genet, 2019 Jul 15. PMID 30985895
  4. De novo variants in Myelin regulatory factor (MYRF) as candidates of a new syndrome of cardiac and urogenital anomalies. Pinz H, et al. Am J Med Genet A, 2018 Apr. PMID 29446546, Free PMC Article
  5. Autosomal dominant nanophthalmos and high hyperopia associated with a C-terminal frameshift variant in MYRF. Siggs OM, et al. Mol Vis, 2019. PMID 31700225, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Two sisters with cardiac-urogenital syndrome secondary to pathogenic splicing variant in the MYRF gene with unaffected parents: A case of gonadal mosaicism?
    Title: Two sisters with cardiac-urogenital syndrome secondary to pathogenic splicing variant in the MYRF gene with unaffected parents: A case of gonadal mosaicism?
  2. Truncation mutations in MYRF underlie primary angle closure glaucoma.
    Title: Truncation mutations in MYRF underlie primary angle closure glaucoma.
  3. Evaluation of MYRF as a candidate gene for primary angle closure glaucoma.
    Title: Evaluation of MYRF as a candidate gene for primary angle closure glaucoma.
  4. Functional mechanisms of MYRF DNA-binding domain mutations implicated in birth defects.
    Title: Functional mechanisms of MYRF DNA-binding domain mutations implicated in birth defects.
  5. MYRF: A Mysterious Membrane-Bound Transcription Factor Involved in Myelin Development and Human Diseases.
    Title: MYRF: A Mysterious Membrane-Bound Transcription Factor Involved in Myelin Development and Human Diseases.
  6. Common Myelin Regulatory Factor Gene Variants Predisposing to Excellence in Sports.
    Title: Common Myelin Regulatory Factor Gene Variants Predisposing to Excellence in Sports.
  7. The genetic and clinical landscape of nanophthalmos and posterior microphthalmos in an Australian cohort.
    Title: The genetic and clinical landscape of nanophthalmos and posterior microphthalmos in an Australian cohort.
  8. Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis.
    Title: Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis.
  9. Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects.
    Title: Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects.
  10. results underline the importance of including SLC18A3 sequencing in the differential diagnostics of fetuses with arthrogryposis, FADS, or LMPS of unknown etiology
    Title: Review of the phenotypic spectrum associated with haploinsufficiency of MYRF.
Submit: New GeneRIF Correction See all GeneRIFs (23)

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Cardiac-urogenital syndrome
MedGen: C4748946 OMIM: 618280 GeneReviews: MYRF-Related Cardiac Urogenital Syndrome
Compare labs
Encephalitis/encephalopathy, mild, with reversible myelin vacuolization
MedGen: C4722446 OMIM: 618113 GeneReviews: Not available
Compare labs
Nanophthalmos 1
MedGen: C1838502 OMIM: 600165 GeneReviews: Not available
Compare labs

EBI GWAS Catalog

Description
An atlas of genetic influences on human blood metabolites.
EBI GWAS Catalog
Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
EBI GWAS Catalog
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
EBI GWAS Catalog

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Replication interactions

Interaction Pubs
Knockdown of chromosome 11 open reading frame 9 (C11orf9) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • KIAA0954, MGC10781

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in central nervous system myelin maintenance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in central nervous system myelin maintenance IEA
Inferred from Electronic Annotation
more info
  
involved_in central nervous system myelin maintenance ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in central nervous system myelination IEA
Inferred from Electronic Annotation
more info
  
involved_in central nervous system myelination ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in oligodendrocyte development IEA
Inferred from Electronic Annotation
more info
  
involved_in oligodendrocyte development ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in oligodendrocyte differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in oligodendrocyte differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of myelination IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of myelination ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of oligodendrocyte differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein autoprocessing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein autoprocessing IEA
Inferred from Electronic Annotation
more info
  
involved_in protein autoprocessing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in response to cocaine IEA
Inferred from Electronic Annotation
more info
  
involved_in response to immobilization stress IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
Preferred Names
myelin regulatory factor
Names
myelin gene regulatory factor

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_047038.1 RefSeqGene

    Range
    5000..40882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001127392.3 → NP_001120864.1  myelin regulatory factor isoform 2 precursor

    See identical proteins and their annotated locations for NP_001120864.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks a 5' exon and uses an alternate 5' terminal exon, compared to variant 1. It encodes isoform 2 which is longer and has a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AB023171, AI366703, AP002380, HY145048, HY148147
    Consensus CDS
    CCDS44622.1
    UniProtKB/Swiss-Prot
    O43582, Q9P1Q6, Q9Y2G1
    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000278836.4, ENST00000278836.10
    Conserved Domains (4) summary
    pfam05224
    Location:393 → 540
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:587 → 647
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:667 → 702
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:1016 → 1147
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  2. NM_013279.4 → NP_037411.1  myelin regulatory factor isoform 1

    See identical proteins and their annotated locations for NP_037411.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AB023171, AF086762, AI366703, AP002380
    Consensus CDS
    CCDS31579.1
    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000265460.5, ENST00000265460.9
    Conserved Domains (4) summary
    pfam05224
    Location:384 → 531
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:578 → 638
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:658 → 693
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:976 → 1107
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    61752636..61788518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005274222.2 → XP_005274279.1  myelin regulatory factor isoform X1

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526870.1, ENST00000856811.1
    Conserved Domains (4) summary
    pfam05224
    Location:393 → 540
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:587 → 647
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:667 → 702
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:1017 → 1148
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  2. XM_005274223.2 → XP_005274280.1  myelin regulatory factor isoform X2

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526865.1, ENST00000856806.1
    Conserved Domains (4) summary
    pfam05224
    Location:393 → 540
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:587 → 647
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:667 → 702
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:1012 → 1143
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  3. XM_005274224.2 → XP_005274281.1  myelin regulatory factor isoform X3

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526859.1, ENST00000856800.1
    Conserved Domains (4) summary
    pfam05224
    Location:393 → 540
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:587 → 647
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:667 → 702
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:1011 → 1142
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  4. XM_005274225.2 → XP_005274282.1  myelin regulatory factor isoform X4

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526858.1, ENST00000856799.1
    Conserved Domains (4) summary
    pfam05224
    Location:393 → 540
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:587 → 647
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:667 → 702
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:990 → 1121
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  5. XM_005274227.2 → XP_005274284.1  myelin regulatory factor isoform X6

    See identical proteins and their annotated locations for XP_005274284.1

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526862.1, ENST00000856803.1
    Conserved Domains (4) summary
    pfam05224
    Location:393 → 540
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:587 → 647
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:667 → 702
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:985 → 1116
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  6. XM_005274226.2 → XP_005274283.1  myelin regulatory factor isoform X5

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526871.1, ENST00000856812.1
    Conserved Domains (4) summary
    pfam05224
    Location:393 → 540
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:587 → 647
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:667 → 702
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:989 → 1120
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  7. XM_047427526.1 → XP_047283482.1  myelin regulatory factor isoform X7

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526860.1, ENST00000856801.1

  8. XM_005274228.2 → XP_005274285.1  myelin regulatory factor isoform X8

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Conserved Domains (4) summary
    pfam05224
    Location:342 → 489
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:536 → 596
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:616 → 651
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:966 → 1097
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  9. XM_047427528.1 → XP_047283484.1  myelin regulatory factor isoform X10

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526863.1, ENST00000856804.1

  10. XM_047427527.1 → XP_047283483.1  myelin regulatory factor isoform X9

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  11. XM_047427529.1 → XP_047283485.1  myelin regulatory factor isoform X11

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526857.1, ENST00000856798.1

  12. XM_047427531.1 → XP_047283487.1  myelin regulatory factor isoform X13

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  13. XM_047427533.1 → XP_047283489.1  myelin regulatory factor isoform X15

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526861.1, ENST00000856802.1

  14. XM_047427532.1 → XP_047283488.1  myelin regulatory factor isoform X14

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  15. XM_047427534.1 → XP_047283490.1  myelin regulatory factor isoform X16

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000526868.1, ENST00000856809.1

  16. XM_047427530.1 → XP_047283486.1  myelin regulatory factor isoform X12

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  17. XM_047427535.1 → XP_047283491.1  myelin regulatory factor isoform X17

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  18. XM_024448677.2 → XP_024304445.1  myelin regulatory factor isoform X18

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Conserved Domains (4) summary
    pfam05224
    Location:246 → 393
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:440 → 500
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:520 → 555
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:870 → 1001
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  19. XM_047427536.1 → XP_047283492.1  myelin regulatory factor isoform X19

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  20. XM_047427537.1 → XP_047283493.1  myelin regulatory factor isoform X20

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  21. XM_047427538.1 → XP_047283494.1  myelin regulatory factor isoform X21

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  22. XM_011545234.3 → XP_011543536.1  myelin regulatory factor isoform X22

    UniProtKB/TrEMBL
    A0A6Q8PHM1
    Related
    ENSP00000502795.1, ENST00000675319.1
    Conserved Domains (4) summary
    pfam05224
    Location:192 → 339
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:386 → 446
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:466 → 501
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:816 → 947
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    61741556..61777435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054369829.1 → XP_054225804.1  myelin regulatory factor isoform X1

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  2. XM_054369830.1 → XP_054225805.1  myelin regulatory factor isoform X2

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  3. XM_054369831.1 → XP_054225806.1  myelin regulatory factor isoform X3

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  4. XM_054369832.1 → XP_054225807.1  myelin regulatory factor isoform X4

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  5. XM_054369834.1 → XP_054225809.1  myelin regulatory factor isoform X6

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  6. XM_054369833.1 → XP_054225808.1  myelin regulatory factor isoform X5

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  7. XM_054369835.1 → XP_054225810.1  myelin regulatory factor isoform X7

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  8. XM_054369836.1 → XP_054225811.1  myelin regulatory factor isoform X8

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  9. XM_054369838.1 → XP_054225813.1  myelin regulatory factor isoform X10

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  10. XM_054369837.1 → XP_054225812.1  myelin regulatory factor isoform X9

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  11. XM_054369839.1 → XP_054225814.1  myelin regulatory factor isoform X11

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  12. XM_054369841.1 → XP_054225816.1  myelin regulatory factor isoform X13

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  13. XM_054369843.1 → XP_054225818.1  myelin regulatory factor isoform X15

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  14. XM_054369842.1 → XP_054225817.1  myelin regulatory factor isoform X14

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  15. XM_054369844.1 → XP_054225819.1  myelin regulatory factor isoform X16

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  16. XM_054369840.1 → XP_054225815.1  myelin regulatory factor isoform X12

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  17. XM_054369845.1 → XP_054225820.1  myelin regulatory factor isoform X17

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  18. XM_054369850.1 → XP_054225825.1  myelin regulatory factor isoform X22

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  19. XM_054369846.1 → XP_054225821.1  myelin regulatory factor isoform X18

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  20. XM_054369847.1 → XP_054225822.1  myelin regulatory factor isoform X19

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  21. XM_054369848.1 → XP_054225823.1  myelin regulatory factor isoform X20

    UniProtKB/TrEMBL
    A0A6Q8PHM1

  22. XM_054369849.1 → XP_054225824.1  myelin regulatory factor isoform X21

    UniProtKB/TrEMBL
    A0A6Q8PHM1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Y2G1.3 GenPept UniProtKB/Swiss-Prot:Q9Y2G1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools