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Gorasp1 golgi reassembly stacking protein 1 [ Mus musculus (house mouse) ]

Gene ID: 74498, updated on 26-Sep-2022

Summary

Official Symbol
Gorasp1provided by MGI
Official Full Name
golgi reassembly stacking protein 1provided by MGI
Primary source
MGI:MGI:1921748
See related
Ensembl:ENSMUSG00000032513 AllianceGenome:MGI:1921748
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P65; GOLPH5; GRASP65; 5430411C10Rik
Summary
Predicted to enable metal ion binding activity. Acts upstream of or within Golgi organization and protein N-linked glycosylation. Located in Golgi apparatus. Is expressed in cortical layer V and hippocampus CA1. Orthologous to human GORASP1 (golgi reassembly stacking protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 25.3), genital fat pad adult (RPKM 21.1) and 28 other tissues See more
Orthologs
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Genomic context

See Gorasp1 in Genome Data Viewer
Location:
9; 9 F4
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (119754739..119766624, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (119925673..119937558, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33701 Neighboring gene sodium channel, voltage-gated, type XI, alpha Neighboring gene predicted gene 2449 Neighboring gene WD repeat domain 48 Neighboring gene tetratricopeptide repeat domain 21A Neighboring gene cysteine-serine-rich nuclear protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within Golgi organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
 
involved_in establishment of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of dendrite morphogenesis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within protein N-linked glycosylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Golgi reassembly-stacking protein 1
Names
golgi peripheral membrane protein p65
golgi reassembly-stacking protein of 65 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028976.2NP_083252.1  Golgi reassembly-stacking protein 1

    See identical proteins and their annotated locations for NP_083252.1

    Status: PROVISIONAL

    Source sequence(s)
    AC124662
    Consensus CDS
    CCDS23619.1
    UniProtKB/Swiss-Prot
    Q91X51, Q9D3L9
    UniProtKB/TrEMBL
    Q3TCN5
    Related
    ENSMUSP00000035099.8, ENSMUST00000035099.9
    Conserved Domains (2) summary
    pfam04495
    Location:68204
    GRASP55_65; GRASP55/65 PDZ-like domain
    cl00117
    Location:1499
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    119754739..119766624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)