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Zfp84 zinc finger protein 84 [ Mus musculus (house mouse) ]

Gene ID: 74352, updated on 7-May-2024

Summary

Official Symbol
Zfp84provided by MGI
Official Full Name
zinc finger protein 84provided by MGI
Primary source
MGI:MGI:107780
See related
Ensembl:ENSMUSG00000046185 AllianceGenome:MGI:107780
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp69; KRAB18; 2210410P13Rik; 4633401C23Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; genitourinary system; and limb mesenchyme. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 4.7), CNS E14 (RPKM 4.6) and 27 other tissues See more
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Genomic context

See Zfp84 in Genome Data Viewer
Location:
7 B1; 7 17.25 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29467977..29480844)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29768552..29781419)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 23103 Neighboring gene STARR-seq mESC enhancer starr_18485 Neighboring gene predicted gene, 38983 Neighboring gene STARR-positive B cell enhancer ABC_E6530 Neighboring gene microRNA 1964 Neighboring gene STARR-seq mESC enhancer starr_18488 Neighboring gene zinc finger protein 30 Neighboring gene predicted gene 6579

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc finger protein 84
Names
zinc finger protein 69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023750.2NP_076239.1  zinc finger protein 84

    See identical proteins and their annotated locations for NP_076239.1

    Status: VALIDATED

    Source sequence(s)
    AC122256, AK034259, AK145426
    Consensus CDS
    CCDS21074.1
    UniProtKB/TrEMBL
    Q9D654
    Related
    ENSMUSP00000032802.5, ENSMUST00000032802.5
    Conserved Domains (5) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:243559
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:447467
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:515540
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    29467977..29480844
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)