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Pop7 processing of precursor 7, ribonuclease P family, (S. cerevisiae) [ Mus musculus (house mouse) ]

Gene ID: 74097, updated on 30-Apr-2024

Summary

Official Symbol
Pop7provided by MGI
Official Full Name
processing of precursor 7, ribonuclease P family, (S. cerevisiae)provided by MGI
Primary source
MGI:MGI:1921347
See related
Ensembl:ENSMUSG00000029715 AllianceGenome:MGI:1921347
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpp20; 0610037N12Rik
Summary
Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic and tRNA 5'-leader removal. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleolus. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Predicted to be active in nucleus. Orthologous to human POP7 (POP7 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 22.5), large intestine adult (RPKM 22.2) and 28 other tissues See more
Orthologs
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Genomic context

See Pop7 in Genome Data Viewer
Location:
5 G2; 5 76.51 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137499701..137500682, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137501439..137502429, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38725 Neighboring gene predicted gene, 36056 Neighboring gene erythropoietin Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:137943213-137943434 Neighboring gene RIKEN cDNA 9130604C24 gene Neighboring gene GRB10 interacting GYF protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables ribonuclease P RNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to ribonuclease P activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA 5'-leader removal ISO
Inferred from Sequence Orthology
more info
 
involved_in tRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
part_of multimeric ribonuclease P complex ISO
Inferred from Sequence Orthology
more info
 
part_of nucleolar ribonuclease P complex IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonuclease MRP complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ribonuclease P protein subunit p20
Names
Pop7 homolog
RNaseP protein p20
NP_083029.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028753.3NP_083029.1  ribonuclease P protein subunit p20

    See identical proteins and their annotated locations for NP_083029.1

    Status: VALIDATED

    Source sequence(s)
    AC148018
    Consensus CDS
    CCDS19768.1
    UniProtKB/Swiss-Prot
    Q9DCH2
    Related
    ENSMUSP00000031728.5, ENSMUST00000031728.5
    Conserved Domains (1) summary
    pfam12328
    Location:33133
    Rpp20; Rpp20 subunit of nuclear RNase MRP and P

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    137499701..137500682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)