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Lmntd1 lamin tail domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 74071, updated on 12-Mar-2023

Summary

Official Symbol
Lmntd1provided by MGI
Official Full Name
lamin tail domain containing 1provided by MGI
Primary source
MGI:MGI:1921321
See related
Ensembl:ENSMUSG00000054966 AllianceGenome:MGI:1921321
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lmna1; Ifltd1; Lmna-rs1; 4933403M22Rik
Summary
Acts upstream of or within cell population proliferation. Located in cytoplasm and nuclear envelope. Orthologous to human LMNTD1 (lamin tail domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 3.5), heart adult (RPKM 1.3) and 4 other tissues See more
Orthologs
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Genomic context

See Lmntd1 in Genome Data Viewer
Location:
6 G3; 6 77.37 cM
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (145311619..145560045, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (145389314..145450767, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lactate dehydrogenase A pseudogene Neighboring gene ribosomal protein L7 pseudogene Neighboring gene predicted gene, 38926 Neighboring gene predicted gene, 23498 Neighboring gene predicted gene 15499 Neighboring gene predicted gene, 25373 Neighboring gene tubulin, alpha 3B Neighboring gene predicted gene 15704 Neighboring gene Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell population proliferation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 
is_active_in nuclear envelope IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
lamin tail domain-containing protein 1
Names
intermediate filament tail domain containing 1
intermediate filament tail domain-containing protein 1
lamin A-related sequence 1
lamin-A-related sequence 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417808.1NP_001404737.1  lamin tail domain-containing protein 1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC153577
  2. NM_001417809.1NP_001404738.1  lamin tail domain-containing protein 1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC153577
  3. NM_001417810.1NP_001404739.1  lamin tail domain-containing protein 1 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC153577
  4. NM_001417811.1NP_001404740.1  lamin tail domain-containing protein 1 isoform d

    Status: VALIDATED

    Source sequence(s)
    AC153577
  5. NM_001417812.1NP_001404741.1  lamin tail domain-containing protein 1 isoform e

    Status: VALIDATED

    Source sequence(s)
    AC153577
  6. NM_028742.3NP_083018.1  lamin tail domain-containing protein 1 isoform a

    See identical proteins and their annotated locations for NP_083018.1

    Status: VALIDATED

    Source sequence(s)
    AC153577
    Consensus CDS
    CCDS20695.1
    UniProtKB/Swiss-Prot
    Q5UE52, Q9D4C1
    Related
    ENSMUSP00000107337.3, ENSMUST00000111708.9
    Conserved Domains (1) summary
    pfam00932
    Location:179284
    LTD; Lamin Tail Domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    145311619..145560045 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506987.5XP_006507050.1  lamin tail domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006507050.1

    Conserved Domains (1) summary
    pfam00932
    Location:204309
    LTD; Lamin Tail Domain
  2. XM_036152362.1XP_036008255.1  lamin tail domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    pfam00932
    Location:178286
    LTD; Lamin Tail Domain
  3. XM_036152366.1XP_036008259.1  lamin tail domain-containing protein 1 isoform X9

  4. XM_017321792.3XP_017177281.1  lamin tail domain-containing protein 1 isoform X7

    Conserved Domains (1) summary
    pfam00932
    Location:119224
    LTD; Lamin Tail Domain
  5. XM_036152365.1XP_036008258.1  lamin tail domain-containing protein 1 isoform X8

  6. XM_006506986.5XP_006507049.1  lamin tail domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006507049.1

    Conserved Domains (1) summary
    pfam00932
    Location:204309
    LTD; Lamin Tail Domain
  7. XM_006506985.5XP_006507048.1  lamin tail domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006507048.1

    Conserved Domains (1) summary
    pfam00932
    Location:204309
    LTD; Lamin Tail Domain
  8. XM_017321788.3XP_017177277.1  lamin tail domain-containing protein 1 isoform X3

    UniProtKB/Swiss-Prot
    Q5UE52, Q9D4C1
    Conserved Domains (1) summary
    pfam00932
    Location:179284
    LTD; Lamin Tail Domain
  9. XM_006506995.5XP_006507058.1  lamin tail domain-containing protein 1 isoform X6

    UniProtKB/TrEMBL
    E9Q8Y6
    Related
    ENSMUSP00000107335.2, ENSMUST00000111706.8
    Conserved Domains (1) summary
    pfam00932
    Location:129234
    LTD; Lamin Tail Domain
  10. XM_036152363.1XP_036008256.1  lamin tail domain-containing protein 1 isoform X4

  11. XM_017321790.1XP_017177279.1  lamin tail domain-containing protein 1 isoform X6

    UniProtKB/TrEMBL
    E9Q8Y6
    Conserved Domains (1) summary
    pfam00932
    Location:129234
    LTD; Lamin Tail Domain
  12. XM_017321786.1XP_017177275.1  lamin tail domain-containing protein 1 isoform X3

    UniProtKB/Swiss-Prot
    Q5UE52, Q9D4C1
    Conserved Domains (1) summary
    pfam00932
    Location:179284
    LTD; Lamin Tail Domain
  13. XM_017321784.1XP_017177273.1  lamin tail domain-containing protein 1 isoform X3

    UniProtKB/Swiss-Prot
    Q5UE52, Q9D4C1
    Conserved Domains (1) summary
    pfam00932
    Location:179284
    LTD; Lamin Tail Domain
  14. XM_036152364.1XP_036008257.1  lamin tail domain-containing protein 1 isoform X5

  15. XM_017321783.1XP_017177272.1  lamin tail domain-containing protein 1 isoform X3

    UniProtKB/Swiss-Prot
    Q5UE52, Q9D4C1
    Conserved Domains (1) summary
    pfam00932
    Location:179284
    LTD; Lamin Tail Domain
  16. XM_017321785.3XP_017177274.1  lamin tail domain-containing protein 1 isoform X3

    UniProtKB/Swiss-Prot
    Q5UE52, Q9D4C1
    Conserved Domains (1) summary
    pfam00932
    Location:179284
    LTD; Lamin Tail Domain
  17. XM_017321787.1XP_017177276.1  lamin tail domain-containing protein 1 isoform X3

    UniProtKB/Swiss-Prot
    Q5UE52, Q9D4C1
    Conserved Domains (1) summary
    pfam00932
    Location:179284
    LTD; Lamin Tail Domain

RNA

  1. XR_004933626.1 RNA Sequence