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UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [ Homo sapiens (human) ]

Gene ID: 7404, updated on 20-Jun-2020

Summary

Official Symbol
UTYprovided by HGNC
Official Full Name
ubiquitously transcribed tetratricopeptide repeat containing, Y-linkedprovided by HGNC
Primary source
HGNC:HGNC:12638
See related
Ensembl:ENSG00000183878 MIM:400009
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UTY1; KDM6C; KDM6AL
Summary
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2012]
Expression
Broad expression in prostate (RPKM 1.9), small intestine (RPKM 1.4) and 20 other tissues See more
Orthologs

Genomic context

See UTY in Genome Data Viewer
Location:
Yq11.221
Exon count:
45
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) Y NC_000024.10 (13231827..13480670, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) Y NC_000024.9 (15360259..15592550, complement)

Chromosome Y - NC_000024.10Genomic Context describing neighboring genes Neighboring gene TGF-beta activated kinase 1/MAP3K7 binding protein 3 pseudogene 1 Neighboring gene developmental pluripotency associated 2 pseudogene 1 Neighboring gene proteasome subunit alpha 6 pseudogene 1 Neighboring gene microRNA 12120 Neighboring gene PC4 and SFRS1 interacting protein 1 pseudogene 2 Neighboring gene thymosin beta 4 Y-linked

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of ubiquitously transcribed tetratricopeptide repeat gene, Y-linked (UTY) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686L12190

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromatin DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
histone demethylase activity (H3-K27 specific) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
histone H3-K27 demethylation IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
MLL3/4 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear chromatin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
histone demethylase UTY
Names
[histone H3]-trimethyl-L-lysine(27) demethylase UTY
ubiquitous TPR motif protein UTY
ubiquitously transcribed TPR gene on Y chromosome
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
ubiquitously-transcribed TPR protein on the Y chromosome
ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein
NP_001245178.1
NP_001245179.1
NP_001245180.1
NP_001245181.1
NP_001245182.1
NP_001245183.1
NP_001245184.1
NP_001245185.1
NP_001245186.1
NP_001245187.1
NP_001245188.1
NP_001245189.1
NP_001245190.1
NP_001245191.1
NP_001245192.1
NP_001245193.1
NP_001245194.1
NP_001245195.1
NP_001245196.1
NP_001245197.1
NP_001245198.1
NP_001245199.1
NP_009056.3
NP_872600.1
NP_872601.1
XP_005262575.1
XP_006724938.1
XP_011529743.1
XP_011529744.1
XP_011529745.1
XP_011529747.1
XP_011529748.1
XP_011529749.1
XP_011529750.1
XP_011529751.1
XP_011529752.1
XP_011529753.1
XP_011529754.1
XP_011529755.1
XP_011529756.1
XP_011529757.1
XP_011529760.1
XP_011529761.1
XP_011529762.1
XP_011529763.1
XP_011529764.1
XP_011529765.1
XP_011529766.1
XP_011529767.1
XP_016885555.1
XP_016885556.1
XP_016885557.1
XP_016885559.1
XP_016885560.1
XP_016885561.1
XP_016885562.1
XP_016885563.1
XP_024308261.1
XP_024308262.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001258249.1NP_001245178.1  histone demethylase UTY isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) encodes the longest isoform (4).
    Source sequence(s)
    AC006376, AC010877, EF612668
    Consensus CDS
    CCDS76079.1
    UniProtKB/TrEMBL
    F4MH35, F5H8B4
    Related
    ENSP00000442047.2, ENST00000545955.5
    Conserved Domains (7) summary
    pfam02373
    Location:11771285
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11431207
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  2. NM_001258250.1NP_001245179.1  histone demethylase UTY isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (5) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, AY934850
    UniProtKB/TrEMBL
    E1NZ93
    Conserved Domains (6) summary
    pfam02373
    Location:9401048
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:906970
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:240275
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:299332
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:298359
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
  3. NM_001258251.1NP_001245180.1  histone demethylase UTY isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (6) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, DQ140388
    Consensus CDS
    CCDS76075.1
    UniProtKB/TrEMBL
    E1U198, F5H3N7
    Related
    ENSP00000445274.2, ENST00000538878.5
    Conserved Domains (7) summary
    pfam02373
    Location:10961204
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10621126
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  4. NM_001258252.1NP_001245181.1  histone demethylase UTY isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks an exon in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (7) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, DQ140389
    Consensus CDS
    CCDS59184.1
    UniProtKB/Swiss-Prot
    O14607
    Related
    ENSP00000372352.4, ENST00000382896.8
    Conserved Domains (7) summary
    pfam02373
    Location:11251233
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10911155
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  5. NM_001258253.1NP_001245182.1  histone demethylase UTY isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (8) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, DQ350457
    UniProtKB/TrEMBL
    E1U1M9
    Conserved Domains (7) summary
    pfam02373
    Location:10961204
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10621126
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  6. NM_001258254.1NP_001245183.1  histone demethylase UTY isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (9) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, DQ140390
    Consensus CDS
    CCDS59185.1
    UniProtKB/Swiss-Prot
    O14607
    Related
    ENSP00000485539.2, ENST00000624098.3
    Conserved Domains (7) summary
    pfam02373
    Location:10011109
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:9671031
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  7. NM_001258255.1NP_001245184.1  histone demethylase UTY isoform 10

    See identical proteins and their annotated locations for NP_001245184.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (10) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612660
    UniProtKB/TrEMBL
    F4MH27
    Conserved Domains (7) summary
    pfam02373
    Location:10011109
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:9671031
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  8. NM_001258256.1NP_001245185.1  histone demethylase UTY isoform 11

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) lacks two exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (11) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612663
    Consensus CDS
    CCDS76078.1
    UniProtKB/TrEMBL
    A0A096LPD8, F4MH30
    Related
    ENSP00000439922.2, ENST00000537580.5
    Conserved Domains (7) summary
    pfam02373
    Location:11251233
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10911155
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  9. NM_001258257.1NP_001245186.1  histone demethylase UTY isoform 12

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (12) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612664
    UniProtKB/TrEMBL
    F4MH31
    Conserved Domains (7) summary
    pfam02373
    Location:9561064
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:922986
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  10. NM_001258258.1NP_001245187.1  histone demethylase UTY isoform 13

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) lacks an exon in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (13) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612673
    Consensus CDS
    CCDS76076.1
    UniProtKB/TrEMBL
    A0A087X0Y2, F4MH40
    Related
    ENSP00000483735.1, ENST00000617789.4
    Conserved Domains (7) summary
    pfam02373
    Location:11321240
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10981162
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  11. NM_001258259.1NP_001245188.1  histone demethylase UTY isoform 14

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (14) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612665
    UniProtKB/TrEMBL
    F4MH32
    Conserved Domains (6) summary
    pfam02373
    Location:10641172
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10301094
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:240275
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:299332
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:298359
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
  12. NM_001258260.1NP_001245189.1  histone demethylase UTY isoform 15

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (15) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612680
    UniProtKB/TrEMBL
    F4MH47
    Conserved Domains (7) summary
    pfam02373
    Location:11101218
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10761140
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  13. NM_001258261.1NP_001245190.1  histone demethylase UTY isoform 16

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (16) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612683
    Consensus CDS
    CCDS76074.1
    UniProtKB/TrEMBL
    F4MH50, F5GWV3
    Related
    ENSP00000441943.2, ENST00000540140.5
    Conserved Domains (5) summary
    pfam02373
    Location:11221230
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10881152
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:103389
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:240275
    TPR; TPR repeat [structural motif]
    pfam13431
    Location:269303
    TPR_17; Tetratricopeptide repeat
  14. NM_001258262.1NP_001245191.1  histone demethylase UTY isoform 17

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (17) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612684
    UniProtKB/TrEMBL
    F4MH51
    Conserved Domains (7) summary
    pfam02373
    Location:10531161
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10191083
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  15. NM_001258263.1NP_001245192.1  histone demethylase UTY isoform 18

    See identical proteins and their annotated locations for NP_001245192.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18) lacks three exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (18) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612693
    UniProtKB/TrEMBL
    F4MH60
    Conserved Domains (7) summary
    pfam02373
    Location:10801188
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10461110
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  16. NM_001258264.1NP_001245193.1  histone demethylase UTY isoform 19

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (19) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612695
    UniProtKB/TrEMBL
    F4MH62
    Conserved Domains (5) summary
    pfam02373
    Location:11091217
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10751139
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    COG0457
    Location:103406
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:240275
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:299332
    TPR_1; Tetratricopeptide repeat
  17. NM_001258265.1NP_001245194.1  histone demethylase UTY isoform 20

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20) lacks six exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (20) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF653189
    Consensus CDS
    CCDS76073.1
    UniProtKB/TrEMBL
    A0A087X248, F4MH91
    Related
    ENSP00000484698.1, ENST00000618474.4
    Conserved Domains (7) summary
    pfam02373
    Location:9971105
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:9631027
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:199226
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:232265
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:231292
    TPR_11; TPR repeat
    pfam13424
    Location:194262
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:186217
    TPR_17; Tetratricopeptide repeat
  18. NM_001258266.1NP_001245195.1  histone demethylase UTY isoform 21

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21) lacks two exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (21) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF653190
    Consensus CDS
    CCDS76077.1
    UniProtKB/TrEMBL
    A0A087X2I9, F4MH92
    Related
    ENSP00000485013.1, ENST00000612274.4
    Conserved Domains (7) summary
    pfam02373
    Location:11001208
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10661130
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  19. NM_001258267.1NP_001245196.1  histone demethylase UTY isoform 22

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 4. The encoded isoform (22) is shorter and has a distinct C-terminus, compared to isoform 4.
    Source sequence(s)
    AC006376, AC010877, DQ341386
    UniProtKB/TrEMBL
    E1U1M3
    Conserved Domains (7) summary
    pfam02373
    Location:10801188
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10461110
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  20. NM_001258268.1NP_001245197.1  histone demethylase UTY isoform 23

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 4. The encoded isoform (23) is shorter and has a distinct C-terminus, compared to isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612662
    UniProtKB/TrEMBL
    F4MH29
    Conserved Domains (7) summary
    pfam02373
    Location:10011109
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:9671031
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  21. NM_001258269.1NP_001245198.1  histone demethylase UTY isoform 24

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 4. The encoded isoform (24) is shorter and has a distinct C-terminus, compared to isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612679
    UniProtKB/TrEMBL
    F4MH46
    Conserved Domains (7) summary
    pfam02373
    Location:10311139
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:9971061
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  22. NM_001258270.1NP_001245199.1  histone demethylase UTY isoform 25

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 4. The encoded isoform (25) is shorter and has a distinct C-terminus, compared to isoform 4.
    Source sequence(s)
    AC006376, AC010877, EF612669
    UniProtKB/TrEMBL
    F4MH36
    Conserved Domains (7) summary
    pfam02373
    Location:9561064
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:922986
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  23. NM_007125.4NP_009056.3  histone demethylase UTY isoform 3

    See identical proteins and their annotated locations for NP_009056.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks two consecutive exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (3) is shorter than isoform 4.
    Source sequence(s)
    AC006376, AC010877, AF000994
    Consensus CDS
    CCDS14783.1
    UniProtKB/Swiss-Prot
    O14607
    Related
    ENSP00000328939.4, ENST00000331397.8
    Conserved Domains (7) summary
    pfam02373
    Location:10801188
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10461110
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  24. NM_182659.1NP_872600.1  histone demethylase UTY isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has multiple differences compared to variant 4, including the use of an alternate 3' UTR. The encoded isoform (2) is shorter than isoform 4.
    Source sequence(s)
    AF000995
    Consensus CDS
    CCDS14784.1
    UniProtKB/Swiss-Prot
    O14607
    Related
    ENSP00000355420.4, ENST00000362096.8
    Conserved Domains (7) summary
    pfam02373
    Location:10801188
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10461110
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  25. NM_182660.1NP_872601.1  histone demethylase UTY isoform 1

    See identical proteins and their annotated locations for NP_872601.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) has multiple differences compared to variant 4, including the use of an alternate 3' UTR. The encoded isoform (1) is shorter and has a distinct C-terminus, compared to isoform 4.
    Source sequence(s)
    AF000996
    Consensus CDS
    CCDS14785.1
    UniProtKB/Swiss-Prot
    O14607
    Related
    ENSP00000330446.5, ENST00000329134.9
    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    pfam13900
    Location:9961040
    GVQW; Putative domain of unknown function

RNA

  1. NR_047596.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, AY769065
  2. NR_047597.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, AY769062
  3. NR_047598.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (28) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, AY769061
  4. NR_047599.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (29) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, DQ350459
  5. NR_047600.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (30) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, DQ350456
  6. NR_047601.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (31) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653168
  7. NR_047602.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (32) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653182
  8. NR_047603.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (33) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653186
  9. NR_047604.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (34) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653191
  10. NR_047605.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (35) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653218
  11. NR_047606.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (36) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685283
  12. NR_047607.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (37) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653224
  13. NR_047608.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (38) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685285
  14. NR_047609.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (39) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685284
  15. NR_047610.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (40) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685287
  16. NR_047611.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (41) lacks two internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685286
  17. NR_047612.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (42) lacks an internal exon compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685288
  18. NR_047613.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (43) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685290
  19. NR_047614.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (44) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685291
  20. NR_047615.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (45) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685292
  21. NR_047616.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (46) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685293
  22. NR_047617.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (47) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685294
  23. NR_047618.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (48) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685295
  24. NR_047619.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (49) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685296
  25. NR_047620.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (50) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685297
  26. NR_047621.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (51) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685298
  27. NR_047622.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (52) lacks two internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685300
  28. NR_047623.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (53) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685301
  29. NR_047624.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (54) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685307
  30. NR_047625.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (55) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685308
  31. NR_047626.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (56) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685309
  32. NR_047627.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (57) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685312
  33. NR_047628.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (58) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685314
  34. NR_047629.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (59) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685316
  35. NR_047630.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (60) lacks four internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF685342
  36. NR_047631.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (61) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EU026310
  37. NR_047632.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (62) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EU026316
  38. NR_047633.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (63) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EU026317
  39. NR_047634.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (64) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EU116348
  40. NR_047635.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (65) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EU116352
  41. NR_047636.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (66) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EU116353
  42. NR_047637.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (67) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EU163942
  43. NR_047638.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (68) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EU163941
  44. NR_047639.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (69) lacks four internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653192
  45. NR_047640.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (70) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653193
  46. NR_047641.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (71) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653196
  47. NR_047642.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (72) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653198
  48. NR_047643.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (73) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653200
  49. NR_047644.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (74) uses an alternate splice site compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653207
  50. NR_047645.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (75) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653209
  51. NR_047646.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (76) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653213
  52. NR_047647.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (77) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC006376, AC010877, EF653217

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000024.10 Reference GRCh38.p13 Primary Assembly

    Range
    13231827..13480670 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011531452.3XP_011529754.1  histone demethylase UTY isoform X11

    Conserved Domains (7) summary
    pfam02373
    Location:10801188
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10461110
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  2. XM_011531451.3XP_011529753.1  histone demethylase UTY isoform X10

    Conserved Domains (7) summary
    pfam02373
    Location:10961204
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10621126
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  3. XM_011531450.3XP_011529752.1  histone demethylase UTY isoform X9

    Conserved Domains (7) summary
    pfam02373
    Location:11101218
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10761140
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  4. XM_011531448.3XP_011529750.1  histone demethylase UTY isoform X7

    Conserved Domains (7) summary
    pfam02373
    Location:11261234
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10921156
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  5. XM_011531447.3XP_011529749.1  histone demethylase UTY isoform X6

    Conserved Domains (7) summary
    pfam02373
    Location:11321240
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10981162
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  6. XM_011531445.3XP_011529747.1  histone demethylase UTY isoform X4

    Conserved Domains (7) summary
    pfam02373
    Location:11481256
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11141178
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  7. XM_011531449.3XP_011529751.1  histone demethylase UTY isoform X8

    Conserved Domains (7) summary
    pfam02373
    Location:11251233
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:10911155
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  8. XM_011531446.3XP_011529748.1  histone demethylase UTY isoform X5

    Conserved Domains (7) summary
    pfam02373
    Location:11411249
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11071171
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  9. XM_011531443.3XP_011529745.1  histone demethylase UTY isoform X3

    Conserved Domains (7) summary
    pfam02373
    Location:11711279
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11371201
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  10. XM_011531442.3XP_011529744.1  histone demethylase UTY isoform X2

    Conserved Domains (7) summary
    pfam02373
    Location:11771285
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11431207
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  11. XM_011531441.3XP_011529743.1  histone demethylase UTY isoform X1

    Conserved Domains (7) summary
    pfam02373
    Location:11931301
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11591223
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  12. XM_017030068.2XP_016885557.1  histone demethylase UTY isoform X19

  13. XM_017030067.2XP_016885556.1  histone demethylase UTY isoform X17

  14. XM_017030066.2XP_016885555.1  histone demethylase UTY isoform X16

  15. XM_011531458.3XP_011529760.1  histone demethylase UTY isoform X15

    Conserved Domains (7) summary
    pfam02373
    Location:11551263
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11211185
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  16. XM_017030074.2XP_016885563.1  histone demethylase UTY isoform X34

    Conserved Domains (7) summary
    pfam02373
    Location:11711279
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11371201
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  17. XM_011531454.3XP_011529756.1  histone demethylase UTY isoform X13

    Conserved Domains (7) summary
    pfam02373
    Location:11931301
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11591223
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  18. XM_011531453.3XP_011529755.1  histone demethylase UTY isoform X12

    Conserved Domains (7) summary
    pfam02373
    Location:11931301
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11591223
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  19. XM_011531455.3XP_011529757.1  histone demethylase UTY isoform X14

    See identical proteins and their annotated locations for XP_011529757.1

    Conserved Domains (7) summary
    pfam02373
    Location:11931301
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11591223
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  20. XM_011531459.3XP_011529761.1  histone demethylase UTY isoform X18

    Conserved Domains (7) summary
    pfam02373
    Location:11931301
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:11591223
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
  21. XM_017030070.2XP_016885559.1  histone demethylase UTY isoform X21

  22. XM_005262518.4XP_005262575.1  histone demethylase UTY isoform X24

    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    cl21464
    Location:11251178
    cupin_like; Conserved domain found in cupin and related proteins
  23. XM_006724875.4XP_006724938.1  histone demethylase UTY isoform X22

    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    cl21464
    Location:11771230
    cupin_like; Conserved domain found in cupin and related proteins
  24. XM_024452493.1XP_024308261.1  histone demethylase UTY isoform X20

    Conserved Domains (3) summary
    COG0457
    Location:103375
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    cl21464
    Location:11931246
    cupin_like; Conserved domain found in cupin and related proteins
  25. XM_017030071.2XP_016885560.1  histone demethylase UTY isoform X26

  26. XM_017030073.2XP_016885562.1  histone demethylase UTY isoform X33

  27. XM_011531465.3XP_011529767.1  histone demethylase UTY isoform X32

    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    pfam13900
    Location:10121056
    GVQW; Putative domain of unknown function
  28. XM_024452494.1XP_024308262.1  histone demethylase UTY isoform X31

    Conserved Domains (2) summary
    COG0457
    Location:103375
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
  29. XM_017030072.2XP_016885561.1  histone demethylase UTY isoform X29

  30. XM_011531464.3XP_011529766.1  histone demethylase UTY isoform X30

    See identical proteins and their annotated locations for XP_011529766.1

    UniProtKB/TrEMBL
    F4MH58
    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    pfam13900
    Location:10411085
    GVQW; Putative domain of unknown function
  31. XM_011531463.3XP_011529765.1  histone demethylase UTY isoform X28

    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    pfam13900
    Location:10571101
    GVQW; Putative domain of unknown function
  32. XM_011531462.3XP_011529764.1  histone demethylase UTY isoform X27

    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    pfam13900
    Location:10711115
    GVQW; Putative domain of unknown function
  33. XM_011531461.3XP_011529763.1  histone demethylase UTY isoform X25

    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    pfam13900
    Location:10931137
    GVQW; Putative domain of unknown function
  34. XM_011531460.3XP_011529762.1  histone demethylase UTY isoform X23

    Conserved Domains (6) summary
    sd00006
    Location:282309
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:315348
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:314375
    TPR_11; TPR repeat
    pfam13424
    Location:202279
    TPR_12; Tetratricopeptide repeat
    pfam13431
    Location:269300
    TPR_17; Tetratricopeptide repeat
    pfam13900
    Location:11091153
    GVQW; Putative domain of unknown function

RNA

  1. XR_001756008.2 RNA Sequence

  2. XR_002958831.1 RNA Sequence

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