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Rftn2 raftlin family member 2 [ Mus musculus (house mouse) ]

Gene ID: 74013, updated on 8-Dec-2018

Summary

Official Symbol
Rftn2provided by MGI
Official Full Name
raftlin family member 2provided by MGI
Primary source
MGI:MGI:1921263
See related
Ensembl:ENSMUSG00000025978
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2700010E02Rik; 3222401M22Rik
Expression
Broad expression in limb E14.5 (RPKM 6.6), frontal lobe adult (RPKM 4.5) and 20 other tissues See more
Orthologs

Genomic context

See Rftn2 in Genome Data Viewer
Location:
1; 1 C1.2
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (55170159..55227065, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (55227003..55283626, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene MOB family member 4, phocein Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g pseudogene Neighboring gene predicted gene 10561 Neighboring gene methionine-tRNA synthetase 2 (mitochondrial) Neighboring gene boule homolog, RNA binding protein Neighboring gene predicted gene 8292

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Homology

Clone Names

  • KIAA0084

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
dsRNA transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to exogenous dsRNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
raftlin-2
Names
raft-linking protein 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356287.1NP_001343216.1  raftlin-2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 5' coding region which results in a frameshift and the use of an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC122223, AC122889
    Conserved Domains (1) summary
    pfam15250
    Location:8331
    Raftlin; Raftlin
  2. NM_001356288.1NP_001343217.1  raftlin-2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks exons in its 5' UTR and 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) his shorter than isoform 1.
    Source sequence(s)
    AC122223, AC122889
    Conserved Domains (1) summary
    pfam15250
    Location:1316
    Raftlin; Raftlin
  3. NM_028713.1NP_082989.1  raftlin-2 isoform 1

    See identical proteins and their annotated locations for NP_082989.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    BC038341
    Consensus CDS
    CCDS14962.1
    UniProtKB/Swiss-Prot
    Q8CHX7
    Related
    ENSMUSP00000027121.8, ENSMUST00000027121.14
    Conserved Domains (1) summary
    pfam15250
    Location:1438
    Raftlin; Raftlin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

    Range
    55170159..55227065 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238611.1XP_011236913.1  raftlin-2 isoform X4

    Conserved Domains (1) summary
    pfam15250
    Location:8331
    Raftlin; Raftlin
  2. XM_017312489.1XP_017167978.1  raftlin-2 isoform X5

    Conserved Domains (1) summary
    pfam15250
    Location:1316
    Raftlin; Raftlin
  3. XM_006496308.3XP_006496371.1  raftlin-2 isoform X1

    Conserved Domains (1) summary
    pfam15250
    Location:1464
    Raftlin; Raftlin
  4. XM_011238612.2XP_011236914.1  raftlin-2 isoform X6

    Conserved Domains (1) summary
    pfam15250
    Location:8304
    Raftlin; Raftlin
  5. XM_006496309.3XP_006496372.1  raftlin-2 isoform X3

    Conserved Domains (1) summary
    pfam15250
    Location:2341
    Raftlin; Raftlin
  6. XM_011238610.2XP_011236912.1  raftlin-2 isoform X2

    Conserved Domains (1) summary
    pfam15250
    Location:1436
    Raftlin; Raftlin
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