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PLAU plasminogen activator, urokinase [ Pan troglodytes (chimpanzee) ]

Gene ID: 738078, updated on 3-Dec-2024
Gene symbol
PLAU
Gene description
plasminogen activator, urokinase
Locus tag
CK820_G0007835
See related
Ensembl:ENSPTRG00000002646
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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See PLAU in Genome Data Viewer
Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (86133212..86141609)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (76753375..76761597)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene N-deacetylase and N-sulfotransferase 2 Neighboring gene calcium/calmodulin dependent protein kinase II gamma Neighboring gene vinculin Neighboring gene adaptor related protein complex 3 subunit mu 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fibrinolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in plasminogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
urokinase-type plasminogen activator
Names
urokinase plasminogen activator
XP_009457026.2
XP_063637970.1

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    86133212..86141609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009458751.4 → XP_009457026.2  urokinase-type plasminogen activator

    UniProtKB/TrEMBL
    A0A2J8NUA3, A0A6D2XWS2, H2Q245, K7AVB0, K7CJD2
    Related
    ENSPTRP00000073321.1
    Conserved Domains (2) summary
    cd00108
    Location:67 → 152
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:179 → 422
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  2. XM_063781900.1 → XP_063637970.1  urokinase-type plasminogen activator

    UniProtKB/TrEMBL
    A0A2J8NUA3, A0A6D2XWS2, H2Q245, K7AVB0, K7CJD2
Nucleotide Protein
Heading Accession and Version

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