U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp383 zinc finger protein 383 [ Mus musculus (house mouse) ]

Gene ID: 73729, updated on 30-Apr-2024

Summary

Official Symbol
Zfp383provided by MGI
Official Full Name
zinc finger protein 383provided by MGI
Primary source
MGI:MGI:1920979
See related
Ensembl:ENSMUSG00000099689 AllianceGenome:MGI:1920979
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110003H10Rik
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nuclear membrane and nucleoplasm. Orthologous to human ZNF383 (zinc finger protein 383). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in whole brain E14.5 (RPKM 5.0), CNS E14 (RPKM 4.9) and 19 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Zfp383 in Genome Data Viewer
Location:
7 B1; 7 17.26 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29607705..29616238)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29908280..29916813)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10434 Neighboring gene zinc finger protein 420 Neighboring gene STARR-seq mESC enhancer starr_18494 Neighboring gene zinc finger protein 27 Neighboring gene STARR-positive B cell enhancer ABC_E9288 Neighboring gene microRNA 7668 Neighboring gene STARR-seq mESC enhancer starr_18496 Neighboring gene zinc finger protein 74 Neighboring gene RIKEN cDNA C230062I16 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:30738577-30738760 Neighboring gene STARR-positive B cell enhancer ABC_E8160 Neighboring gene predicted gene, 57504 Neighboring gene macrophage migration inhibitory factor, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243908.1NP_001230837.1  zinc finger protein 383

    Status: VALIDATED

    Source sequence(s)
    AC149283
    Consensus CDS
    CCDS80690.1
    UniProtKB/TrEMBL
    A0A087WRR7
    Related
    ENSMUSP00000140742.2, ENSMUST00000186475.2
    Conserved Domains (6) summary
    smart00349
    Location:2787
    KRAB; krueppel associated box
    COG5048
    Location:246490
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327347
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:437459
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:2766
    KRAB; KRAB box
    pfam13465
    Location:367392
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    29607705..29616238
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250725.2XP_011249027.1  zinc finger protein 383 isoform X2

    Conserved Domains (5) summary
    smart00349
    Location:1272
    KRAB; krueppel associated box
    COG5048
    Location:231475
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:312332
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:170192
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:212237
    zf-H2C2_2; Zinc-finger double domain
  2. XM_006540391.1XP_006540454.1  zinc finger protein 383 isoform X1

    Conserved Domains (5) summary
    smart00349
    Location:3595
    KRAB; krueppel associated box
    COG5048
    Location:254498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:335355
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:193215
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:235260
    zf-H2C2_2; Zinc-finger double domain